DAR - Bologna Biocomputing Group

Search summary (EC number: 3.1.4.53)

Number of enzymes:	3
Number of disease:	5
Number of reactomes:	3
Number of reactions:	3

Search results (EC number: 3.1.4.53)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0012205	PDE8B	O95263	3.1.4.53	R-HSA-418555 R-HSA-418555 Reactome Name: G alpha (s) signalling events See in Reactome	R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome	Signal Transduction	R-HSA-418553 ( R-HSA-418555 ) R-HSA-418553 Reaction Name: cAMP degradation by Phosphodiesterases See in Reactome
MONDO:0012505	PDE11A	Q9HCR9	3.1.4.53 3.1.4.35	R-HSA-418457 R-HSA-418457 Reactome Name: cGMP effects See in Reactome R-HSA-418555 R-HSA-418555 Reactome Name: G alpha (s) signalling events See in Reactome	R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-392154 R-HSA-392154 Reactome Name: Nitric oxide stimulates guanylate cyclase See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-418346 R-HSA-418346 Reactome Name: Platelet homeostasis See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Hemostasis Signal Transduction	R-HSA-418456 ( R-HSA-418457 ) R-HSA-418456 Reaction Name: cGMP is degraded by PDEs See in Reactome R-HSA-418553 ( R-HSA-418555 ) R-HSA-418553 Reaction Name: cAMP degradation by Phosphodiesterases See in Reactome
MONDO:0013616	PDE8B	O95263	3.1.4.53	R-HSA-418555 R-HSA-418555 Reactome Name: G alpha (s) signalling events See in Reactome	R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome	Signal Transduction	R-HSA-418553 ( R-HSA-418555 ) R-HSA-418553 Reaction Name: cAMP degradation by Phosphodiesterases See in Reactome
MONDO:0013822	PDE4D	Q08499	3.1.4.53	R-HSA-180024 R-HSA-180024 Reactome Name: DARPP-32 events See in Reactome R-HSA-418555 R-HSA-418555 Reactome Name: G alpha (s) signalling events See in Reactome	R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome	Signal Transduction	R-HSA-111962 ( R-HSA-180024 ) R-HSA-111962 Reaction Name: PDE4A,C,D hydrolyse cAMP See in Reactome R-HSA-418553 ( R-HSA-418555 ) R-HSA-418553 Reaction Name: cAMP degradation by Phosphodiesterases See in Reactome
MONDO:0014298	PDE4D	Q08499	3.1.4.53	R-HSA-180024 R-HSA-180024 Reactome Name: DARPP-32 events See in Reactome R-HSA-418555 R-HSA-418555 Reactome Name: G alpha (s) signalling events See in Reactome	R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome	Signal Transduction	R-HSA-111962 ( R-HSA-180024 ) R-HSA-111962 Reaction Name: PDE4A,C,D hydrolyse cAMP See in Reactome R-HSA-418553 ( R-HSA-418555 ) R-HSA-418553 Reaction Name: cAMP degradation by Phosphodiesterases See in Reactome