DAR - Bologna Biocomputing Group

Search summary (EC number: 3.1.4.12)

Number of enzymes:	2
Number of disease:	5
Number of reactomes:	1
Number of reactions:	2

Search results (EC number: 3.1.4.12)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0001071	SMPD1	P17405	3.1.4.12	R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-1605797 ( R-HSA-1660662 ) R-HSA-1605797 Reaction Name: Sphingomyelin phosphodiesterase (SMPD1) hydrolyses sphingomyelin to ceramide (lysosome) See in Reactome
MONDO:0009756	SMPD1	P17405	3.1.4.12	R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-1605797 ( R-HSA-1660662 ) R-HSA-1605797 Reaction Name: Sphingomyelin phosphodiesterase (SMPD1) hydrolyses sphingomyelin to ceramide (lysosome) See in Reactome
MONDO:0011144	SMPD1	P17405	3.1.4.12	R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-1605797 ( R-HSA-1660662 ) R-HSA-1605797 Reaction Name: Sphingomyelin phosphodiesterase (SMPD1) hydrolyses sphingomyelin to ceramide (lysosome) See in Reactome
MONDO:0011871	SMPD1	P17405	3.1.4.12	R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-1605797 ( R-HSA-1660662 ) R-HSA-1605797 Reaction Name: Sphingomyelin phosphodiesterase (SMPD1) hydrolyses sphingomyelin to ceramide (lysosome) See in Reactome
MONDO:0032838	SMPD4	Q9NXE4	3.1.4.12	R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-1606288 ( R-HSA-1660662 ) R-HSA-1606288 Reaction Name: Sphingomyelin phosphodiesterase 4 (SMPD4) hydrolyses sphingomyelin to ceramide (ER membrane) See in Reactome