DAR - Bologna Biocomputing Group

Search summary (EC number: 3.1.3.95)

Number of enzymes:	2
Number of disease:	2
Number of reactomes:	4
Number of reactions:	17

Search results (EC number: 3.1.3.95)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0010683	MTM1	Q13496	3.1.3.64 3.1.3.95	R-HSA-1660499 R-HSA-1660499 Reactome Name: Synthesis of PIPs at the plasma membrane See in Reactome R-HSA-1660516 R-HSA-1660516 Reactome Name: Synthesis of PIPs at the early endosome membrane See in Reactome R-HSA-1660517 R-HSA-1660517 Reactome Name: Synthesis of PIPs at the late endosome membrane See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-1483255 R-HSA-1483255 Reactome Name: PI Metabolism See in Reactome	Metabolism	R-HSA-1675795 ( R-HSA-1660517 ) R-HSA-1675795 Reaction Name: PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane See in Reactome R-HSA-1675994 ( R-HSA-1660499 ) R-HSA-1675994 Reaction Name: PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane See in Reactome R-HSA-1676065 ( R-HSA-1660517 ) R-HSA-1676065 Reaction Name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane See in Reactome R-HSA-1676105 ( R-HSA-1660516 ) R-HSA-1676105 Reaction Name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane See in Reactome R-HSA-1676141 ( R-HSA-1660516 ) R-HSA-1676141 Reaction Name: PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane See in Reactome R-HSA-1676203 ( R-HSA-1660499 ) R-HSA-1676203 Reaction Name: PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane See in Reactome R-HSA-6809680 ( R-HSA-1660516 ) R-HSA-6809680 Reaction Name: MTMR12 binds MTM1 See in Reactome R-HSA-6809720 ( R-HSA-1660516 ) R-HSA-6809720 Reaction Name: PI3P is dephosphorylated to PI by MTM1:MTMR12 See in Reactome
MONDO:0011066	MTMR2	Q13614	3.1.3.64 3.1.3.95	R-HSA-1660499 R-HSA-1660499 Reactome Name: Synthesis of PIPs at the plasma membrane See in Reactome R-HSA-1483248 R-HSA-1483248 Reactome Name: Synthesis of PIPs at the ER membrane See in Reactome R-HSA-1660516 R-HSA-1660516 Reactome Name: Synthesis of PIPs at the early endosome membrane See in Reactome R-HSA-1660517 R-HSA-1660517 Reactome Name: Synthesis of PIPs at the late endosome membrane See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-1483255 R-HSA-1483255 Reactome Name: PI Metabolism See in Reactome	Metabolism	R-HSA-1675795 ( R-HSA-1660517 ) R-HSA-1675795 Reaction Name: PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane See in Reactome R-HSA-1676065 ( R-HSA-1660517 ) R-HSA-1676065 Reaction Name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane See in Reactome R-HSA-1676105 ( R-HSA-1660516 ) R-HSA-1676105 Reaction Name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane See in Reactome R-HSA-1676141 ( R-HSA-1660516 ) R-HSA-1676141 Reaction Name: PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane See in Reactome R-HSA-6809707 ( R-HSA-1660516 ) R-HSA-6809707 Reaction Name: MTMR12 binds MTMR2 See in Reactome R-HSA-6809764 ( R-HSA-1483248 ) R-HSA-6809764 Reaction Name: SBF1 binds MTMR2 See in Reactome R-HSA-6809777 ( R-HSA-1483248 ) R-HSA-6809777 Reaction Name: PI3P is dephosphorylated to PI by MTMR2:SBF1 See in Reactome R-HSA-6809778 ( R-HSA-1483248 ) R-HSA-6809778 Reaction Name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 See in Reactome R-HSA-6809785 ( R-HSA-1660499 ) R-HSA-6809785 Reaction Name: MTMR2 dimerizes See in Reactome R-HSA-6809793 ( R-HSA-1660499 ) R-HSA-6809793 Reaction Name: MTMR2 binds SBF2 See in Reactome R-HSA-6809944 ( R-HSA-1660499 ) R-HSA-6809944 Reaction Name: PI(3,5)P2 is dephosphorylated to PI5P by the MTMR2:SBF2 tetramer at the plasma membrane See in Reactome R-HSA-6809975 ( R-HSA-1660499 ) R-HSA-6809975 Reaction Name: PI3P is dephosphorylated to PI by the MTMR2:SBF2 tetramer at the plasma membrane See in Reactome R-HSA-6810030 ( R-HSA-1660516 ) R-HSA-6810030 Reaction Name: MTMR2 binds MTMR10 See in Reactome