DAR - Bologna Biocomputing Group

Search summary (EC number: 3.1.1.23)

Number of enzymes:	2
Number of disease:	2
Number of reactomes:	2
Number of reactions:	9

Search results (EC number: 3.1.1.23)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0012984	ABHD12	Q8N2K0	3.1.1.23 3.1.-.-	R-HSA-426048 R-HSA-426048 Reactome Name: Arachidonate production from DAG See in Reactome	R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-76002 R-HSA-76002 Reactome Name: Platelet activation, signaling and aggregation See in Reactome R-HSA-416476 R-HSA-416476 Reactome Name: G alpha (q) signalling events See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-114508 R-HSA-114508 Reactome Name: Effects of PIP2 hydrolysis See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Hemostasis Signal Transduction	R-HSA-5694462 ( R-HSA-426048 ) R-HSA-5694462 Reaction Name: ABHD6,12 hydrolyse 3AG See in Reactome
MONDO:0014431	LIPE	Q05469	3.1.1.23 3.1.1.79	R-HSA-163560 R-HSA-163560 Reactome Name: Triglyceride catabolism See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8979227 R-HSA-8979227 Reactome Name: Triglyceride metabolism See in Reactome	Metabolism	R-HSA-163402 ( R-HSA-163560 ) R-HSA-163402 Reaction Name: diacylglycerol + H2O -> 2-acylglycerol + fatty acid See in Reactome R-HSA-163416 ( R-HSA-163560 ) R-HSA-163416 Reaction Name: hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP See in Reactome R-HSA-163432 ( R-HSA-163560 ) R-HSA-163432 Reaction Name: cholesterol ester + H2O -> cholesterol + fatty acid See in Reactome R-HSA-163489 ( R-HSA-163560 ) R-HSA-163489 Reaction Name: phosphorylated HSL + H2O -> HSL + orthophosphate See in Reactome R-HSA-163549 ( R-HSA-163560 ) R-HSA-163549 Reaction Name: phosphorylated HSL dimer + FABP4 -> phosphorylated HSL dimer:FABP4 complex See in Reactome R-HSA-163551 ( R-HSA-163560 ) R-HSA-163551 Reaction Name: triacylglycerol + H2O -> diacylglycerol + fatty acid See in Reactome R-HSA-163554 ( R-HSA-163560 ) R-HSA-163554 Reaction Name: Phosphorylated HSL dimer translocates from the cytosol to the lipid particle See in Reactome R-HSA-163602 ( R-HSA-163560 ) R-HSA-163602 Reaction Name: 2 phosphorylated HSL monomers -> phosphorylated HSL dimer See in Reactome