Number of enzymes: | 8 |
Number of disease: | 14 |
Number of reactomes: | 19 |
Number of reactions: | 51 |
DiseaseID | Gene | UniProt | EC numbers | Reactomes | Expanded Reactomes | Reactome roots | Reactions |
---|---|---|---|---|---|---|---|
MONDO:0005012 | CDK4 | P11802 | 2.7.11.22 |
R-HSA-2559585 R-HSA-2559580 R-HSA-2559582 R-HSA-381340 R-HSA-912446 R-HSA-9616222 R-HSA-8878166 R-HSA-8849470 R-HSA-69231 R-HSA-75815 R-HSA-3214858 R-HSA-187577 |
R-HSA-8848021 R-HSA-2559583 R-HSA-9006927 R-HSA-1640170 R-HSA-1266738 R-HSA-73857 R-HSA-212436 R-HSA-74160 R-HSA-2262752 R-HSA-69236 R-HSA-69278 R-HSA-1474165 R-HSA-453279 R-HSA-8953897 R-HSA-3247509 R-HSA-69656 R-HSA-69206 R-HSA-69202 R-HSA-69242 R-HSA-1500620 R-HSA-4839726 R-HSA-162582 |
Cell Cycle Developmental Biology Gene expression (Transcription) Reproduction Cellular responses to stimuli Chromatin organization Signal Transduction |
R-HSA-1226094
(
R-HSA-69231
) R-HSA-1226095 ( R-HSA-69231 ) R-HSA-182594 ( R-HSA-2559580; R-HSA-2559582; R-HSA-2559585; R-HSA-69231 ) R-HSA-3215385 ( R-HSA-3214858 ) R-HSA-3215426 ( R-HSA-3214858 ) R-HSA-5205799 ( R-HSA-3214858 ) R-HSA-5205861 ( R-HSA-3214858 ) R-HSA-5216234 ( R-HSA-3214858 ) R-HSA-560510 ( R-HSA-381340 ) R-HSA-5661117 ( R-HSA-3214858 ) R-HSA-69227 ( R-HSA-69231 ) R-HSA-75820 ( R-HSA-75815 ) R-HSA-75822 ( R-HSA-75815 ) R-HSA-8848414 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848436 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8941895 ( R-HSA-69231 ) R-HSA-8941915 ( R-HSA-69231 ) R-HSA-8942607 ( R-HSA-69231 ) R-HSA-8942803 ( R-HSA-69231 ) R-HSA-8942836 ( R-HSA-69231 ) R-HSA-9008412 ( R-HSA-8878166 ) R-HSA-9018017 ( R-HSA-69231 ) R-HSA-912429 ( R-HSA-912446 ) R-HSA-912458 ( R-HSA-912446 ) R-HSA-912496 ( R-HSA-912446 ) R-HSA-912503 ( R-HSA-912446 ) R-HSA-9624112 ( R-HSA-9616222 ) R-HSA-9754130 ( R-HSA-69231 ) |
MONDO:0005061 | CDK4 | P11802 | 2.7.11.22 |
R-HSA-2559585 R-HSA-2559580 R-HSA-2559582 R-HSA-381340 R-HSA-912446 R-HSA-9616222 R-HSA-8878166 R-HSA-8849470 R-HSA-69231 R-HSA-75815 R-HSA-3214858 R-HSA-187577 |
R-HSA-8848021 R-HSA-2559583 R-HSA-9006927 R-HSA-1640170 R-HSA-1266738 R-HSA-73857 R-HSA-212436 R-HSA-74160 R-HSA-2262752 R-HSA-69236 R-HSA-69278 R-HSA-1474165 R-HSA-453279 R-HSA-8953897 R-HSA-3247509 R-HSA-69656 R-HSA-69206 R-HSA-69202 R-HSA-69242 R-HSA-1500620 R-HSA-4839726 R-HSA-162582 |
Cell Cycle Developmental Biology Gene expression (Transcription) Reproduction Cellular responses to stimuli Chromatin organization Signal Transduction |
R-HSA-1226094
(
R-HSA-69231
) R-HSA-1226095 ( R-HSA-69231 ) R-HSA-182594 ( R-HSA-2559580; R-HSA-2559582; R-HSA-2559585; R-HSA-69231 ) R-HSA-3215385 ( R-HSA-3214858 ) R-HSA-3215426 ( R-HSA-3214858 ) R-HSA-5205799 ( R-HSA-3214858 ) R-HSA-5205861 ( R-HSA-3214858 ) R-HSA-5216234 ( R-HSA-3214858 ) R-HSA-560510 ( R-HSA-381340 ) R-HSA-5661117 ( R-HSA-3214858 ) R-HSA-69227 ( R-HSA-69231 ) R-HSA-75820 ( R-HSA-75815 ) R-HSA-75822 ( R-HSA-75815 ) R-HSA-8848414 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848436 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8941895 ( R-HSA-69231 ) R-HSA-8941915 ( R-HSA-69231 ) R-HSA-8942607 ( R-HSA-69231 ) R-HSA-8942803 ( R-HSA-69231 ) R-HSA-8942836 ( R-HSA-69231 ) R-HSA-9008412 ( R-HSA-8878166 ) R-HSA-9018017 ( R-HSA-69231 ) R-HSA-912429 ( R-HSA-912446 ) R-HSA-912458 ( R-HSA-912446 ) R-HSA-912496 ( R-HSA-912446 ) R-HSA-912503 ( R-HSA-912446 ) R-HSA-9624112 ( R-HSA-9616222 ) R-HSA-9754130 ( R-HSA-69231 ) |
MONDO:0005061 | CDK12 | Q9NYV4 |
2.7.11.22 2.7.11.23 |
R-HSA-6796648 |
R-HSA-212436 R-HSA-3700989 R-HSA-74160 R-HSA-73857 |
Gene expression (Transcription) |
R-HSA-6797090
(
R-HSA-212436;
R-HSA-6796648
) R-HSA-6797606 ( R-HSA-212436; R-HSA-6796648 ) R-HSA-6797616 ( R-HSA-212436; R-HSA-6796648 ) R-HSA-6797712 ( R-HSA-212436; R-HSA-6796648 ) |
MONDO:0009693 | CDK4 | P11802 | 2.7.11.22 |
R-HSA-2559585 R-HSA-2559580 R-HSA-2559582 R-HSA-381340 R-HSA-912446 R-HSA-9616222 R-HSA-8878166 R-HSA-8849470 R-HSA-69231 R-HSA-75815 R-HSA-3214858 R-HSA-187577 |
R-HSA-8848021 R-HSA-2559583 R-HSA-9006927 R-HSA-1640170 R-HSA-1266738 R-HSA-73857 R-HSA-212436 R-HSA-74160 R-HSA-2262752 R-HSA-69236 R-HSA-69278 R-HSA-1474165 R-HSA-453279 R-HSA-8953897 R-HSA-3247509 R-HSA-69656 R-HSA-69206 R-HSA-69202 R-HSA-69242 R-HSA-1500620 R-HSA-4839726 R-HSA-162582 |
Cell Cycle Developmental Biology Gene expression (Transcription) Reproduction Cellular responses to stimuli Chromatin organization Signal Transduction |
R-HSA-1226094
(
R-HSA-69231
) R-HSA-1226095 ( R-HSA-69231 ) R-HSA-182594 ( R-HSA-2559580; R-HSA-2559582; R-HSA-2559585; R-HSA-69231 ) R-HSA-3215385 ( R-HSA-3214858 ) R-HSA-3215426 ( R-HSA-3214858 ) R-HSA-5205799 ( R-HSA-3214858 ) R-HSA-5205861 ( R-HSA-3214858 ) R-HSA-5216234 ( R-HSA-3214858 ) R-HSA-560510 ( R-HSA-381340 ) R-HSA-5661117 ( R-HSA-3214858 ) R-HSA-69227 ( R-HSA-69231 ) R-HSA-75820 ( R-HSA-75815 ) R-HSA-75822 ( R-HSA-75815 ) R-HSA-8848414 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848436 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8941895 ( R-HSA-69231 ) R-HSA-8941915 ( R-HSA-69231 ) R-HSA-8942607 ( R-HSA-69231 ) R-HSA-8942803 ( R-HSA-69231 ) R-HSA-8942836 ( R-HSA-69231 ) R-HSA-9008412 ( R-HSA-8878166 ) R-HSA-9018017 ( R-HSA-69231 ) R-HSA-912429 ( R-HSA-912446 ) R-HSA-912458 ( R-HSA-912446 ) R-HSA-912496 ( R-HSA-912446 ) R-HSA-912503 ( R-HSA-912446 ) R-HSA-9624112 ( R-HSA-9616222 ) R-HSA-9754130 ( R-HSA-69231 ) |
MONDO:0010396 | CDKL5 | O76039 | 2.7.11.22 | ||||
MONDO:0010726 | CDKL5 | O76039 | 2.7.11.22 | ||||
MONDO:0012183 | CDK4 | P11802 | 2.7.11.22 |
R-HSA-2559585 R-HSA-2559580 R-HSA-2559582 R-HSA-381340 R-HSA-912446 R-HSA-9616222 R-HSA-8878166 R-HSA-8849470 R-HSA-69231 R-HSA-75815 R-HSA-3214858 R-HSA-187577 |
R-HSA-8848021 R-HSA-2559583 R-HSA-9006927 R-HSA-1640170 R-HSA-1266738 R-HSA-73857 R-HSA-212436 R-HSA-74160 R-HSA-2262752 R-HSA-69236 R-HSA-69278 R-HSA-1474165 R-HSA-453279 R-HSA-8953897 R-HSA-3247509 R-HSA-69656 R-HSA-69206 R-HSA-69202 R-HSA-69242 R-HSA-1500620 R-HSA-4839726 R-HSA-162582 |
Cell Cycle Developmental Biology Gene expression (Transcription) Reproduction Cellular responses to stimuli Chromatin organization Signal Transduction |
R-HSA-1226094
(
R-HSA-69231
) R-HSA-1226095 ( R-HSA-69231 ) R-HSA-182594 ( R-HSA-2559580; R-HSA-2559582; R-HSA-2559585; R-HSA-69231 ) R-HSA-3215385 ( R-HSA-3214858 ) R-HSA-3215426 ( R-HSA-3214858 ) R-HSA-5205799 ( R-HSA-3214858 ) R-HSA-5205861 ( R-HSA-3214858 ) R-HSA-5216234 ( R-HSA-3214858 ) R-HSA-560510 ( R-HSA-381340 ) R-HSA-5661117 ( R-HSA-3214858 ) R-HSA-69227 ( R-HSA-69231 ) R-HSA-75820 ( R-HSA-75815 ) R-HSA-75822 ( R-HSA-75815 ) R-HSA-8848414 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848436 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8941895 ( R-HSA-69231 ) R-HSA-8941915 ( R-HSA-69231 ) R-HSA-8942607 ( R-HSA-69231 ) R-HSA-8942803 ( R-HSA-69231 ) R-HSA-8942836 ( R-HSA-69231 ) R-HSA-9008412 ( R-HSA-8878166 ) R-HSA-9018017 ( R-HSA-69231 ) R-HSA-912429 ( R-HSA-912446 ) R-HSA-912458 ( R-HSA-912446 ) R-HSA-912496 ( R-HSA-912446 ) R-HSA-912503 ( R-HSA-912446 ) R-HSA-9624112 ( R-HSA-9616222 ) R-HSA-9754130 ( R-HSA-69231 ) |
MONDO:0014484 | CDK6 | Q00534 | 2.7.11.22 |
R-HSA-2559585 R-HSA-8934593 R-HSA-2559580 R-HSA-69231 R-HSA-2559582 |
R-HSA-453279 R-HSA-8953897 R-HSA-2559583 R-HSA-212436 R-HSA-74160 R-HSA-2262752 R-HSA-8878171 R-HSA-69236 R-HSA-69278 R-HSA-1640170 R-HSA-73857 |
Cellular responses to stimuli Gene expression (Transcription) Cell Cycle |
R-HSA-1226094
(
R-HSA-69231
) R-HSA-1226095 ( R-HSA-69231 ) R-HSA-182594 ( R-HSA-2559580; R-HSA-2559582; R-HSA-2559585; R-HSA-69231 ) R-HSA-69227 ( R-HSA-69231 ) R-HSA-8938853 ( R-HSA-212436; R-HSA-8934593 ) R-HSA-8941895 ( R-HSA-69231 ) R-HSA-8941915 ( R-HSA-69231 ) R-HSA-8942607 ( R-HSA-69231 ) R-HSA-8942803 ( R-HSA-69231 ) R-HSA-8942836 ( R-HSA-69231 ) R-HSA-9018017 ( R-HSA-69231 ) R-HSA-9754129 ( R-HSA-69231 ) |
MONDO:0015356 | CDK4 | P11802 | 2.7.11.22 |
R-HSA-2559585 R-HSA-2559580 R-HSA-2559582 R-HSA-381340 R-HSA-912446 R-HSA-9616222 R-HSA-8878166 R-HSA-8849470 R-HSA-69231 R-HSA-75815 R-HSA-3214858 R-HSA-187577 |
R-HSA-8848021 R-HSA-2559583 R-HSA-9006927 R-HSA-1640170 R-HSA-1266738 R-HSA-73857 R-HSA-212436 R-HSA-74160 R-HSA-2262752 R-HSA-69236 R-HSA-69278 R-HSA-1474165 R-HSA-453279 R-HSA-8953897 R-HSA-3247509 R-HSA-69656 R-HSA-69206 R-HSA-69202 R-HSA-69242 R-HSA-1500620 R-HSA-4839726 R-HSA-162582 |
Cell Cycle Developmental Biology Gene expression (Transcription) Reproduction Cellular responses to stimuli Chromatin organization Signal Transduction |
R-HSA-1226094
(
R-HSA-69231
) R-HSA-1226095 ( R-HSA-69231 ) R-HSA-182594 ( R-HSA-2559580; R-HSA-2559582; R-HSA-2559585; R-HSA-69231 ) R-HSA-3215385 ( R-HSA-3214858 ) R-HSA-3215426 ( R-HSA-3214858 ) R-HSA-5205799 ( R-HSA-3214858 ) R-HSA-5205861 ( R-HSA-3214858 ) R-HSA-5216234 ( R-HSA-3214858 ) R-HSA-560510 ( R-HSA-381340 ) R-HSA-5661117 ( R-HSA-3214858 ) R-HSA-69227 ( R-HSA-69231 ) R-HSA-75820 ( R-HSA-75815 ) R-HSA-75822 ( R-HSA-75815 ) R-HSA-8848414 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848436 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8941895 ( R-HSA-69231 ) R-HSA-8941915 ( R-HSA-69231 ) R-HSA-8942607 ( R-HSA-69231 ) R-HSA-8942803 ( R-HSA-69231 ) R-HSA-8942836 ( R-HSA-69231 ) R-HSA-9008412 ( R-HSA-8878166 ) R-HSA-9018017 ( R-HSA-69231 ) R-HSA-912429 ( R-HSA-912446 ) R-HSA-912458 ( R-HSA-912446 ) R-HSA-912496 ( R-HSA-912446 ) R-HSA-912503 ( R-HSA-912446 ) R-HSA-9624112 ( R-HSA-9616222 ) R-HSA-9754130 ( R-HSA-69231 ) |
MONDO:0018614 | CDK19 | Q9BWU1 | 2.7.11.22 |
R-HSA-1989781 R-HSA-381340 |
R-HSA-556833 R-HSA-400206 R-HSA-1430728 R-HSA-1266738 |
Metabolism Developmental Biology |
R-HSA-1183003
(
R-HSA-381340
) R-HSA-1183058 ( R-HSA-381340 ) R-HSA-381309 ( R-HSA-381340 ) R-HSA-560472 ( R-HSA-381340 ) R-HSA-560473 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560491 ( R-HSA-381340 ) R-HSA-560493 ( R-HSA-381340 ) R-HSA-560498 ( R-HSA-381340 ) R-HSA-560510 ( R-HSA-381340 ) R-HSA-560517 ( R-HSA-1989781; R-HSA-381340 ) |
MONDO:0019438 | CDK4 | P11802 | 2.7.11.22 |
R-HSA-2559585 R-HSA-2559580 R-HSA-2559582 R-HSA-381340 R-HSA-912446 R-HSA-9616222 R-HSA-8878166 R-HSA-8849470 R-HSA-69231 R-HSA-75815 R-HSA-3214858 R-HSA-187577 |
R-HSA-8848021 R-HSA-2559583 R-HSA-9006927 R-HSA-1640170 R-HSA-1266738 R-HSA-73857 R-HSA-212436 R-HSA-74160 R-HSA-2262752 R-HSA-69236 R-HSA-69278 R-HSA-1474165 R-HSA-453279 R-HSA-8953897 R-HSA-3247509 R-HSA-69656 R-HSA-69206 R-HSA-69202 R-HSA-69242 R-HSA-1500620 R-HSA-4839726 R-HSA-162582 |
Cell Cycle Developmental Biology Gene expression (Transcription) Reproduction Cellular responses to stimuli Chromatin organization Signal Transduction |
R-HSA-1226094
(
R-HSA-69231
) R-HSA-1226095 ( R-HSA-69231 ) R-HSA-182594 ( R-HSA-2559580; R-HSA-2559582; R-HSA-2559585; R-HSA-69231 ) R-HSA-3215385 ( R-HSA-3214858 ) R-HSA-3215426 ( R-HSA-3214858 ) R-HSA-5205799 ( R-HSA-3214858 ) R-HSA-5205861 ( R-HSA-3214858 ) R-HSA-5216234 ( R-HSA-3214858 ) R-HSA-560510 ( R-HSA-381340 ) R-HSA-5661117 ( R-HSA-3214858 ) R-HSA-69227 ( R-HSA-69231 ) R-HSA-75820 ( R-HSA-75815 ) R-HSA-75822 ( R-HSA-75815 ) R-HSA-8848414 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8848436 ( R-HSA-187577; R-HSA-8849470 ) R-HSA-8941895 ( R-HSA-69231 ) R-HSA-8941915 ( R-HSA-69231 ) R-HSA-8942607 ( R-HSA-69231 ) R-HSA-8942803 ( R-HSA-69231 ) R-HSA-8942836 ( R-HSA-69231 ) R-HSA-9008412 ( R-HSA-8878166 ) R-HSA-9018017 ( R-HSA-69231 ) R-HSA-912429 ( R-HSA-912446 ) R-HSA-912458 ( R-HSA-912446 ) R-HSA-912496 ( R-HSA-912446 ) R-HSA-912503 ( R-HSA-912446 ) R-HSA-9624112 ( R-HSA-9616222 ) R-HSA-9754130 ( R-HSA-69231 ) |
MONDO:0030059 | CDK19 | Q9BWU1 | 2.7.11.22 |
R-HSA-1989781 R-HSA-381340 |
R-HSA-556833 R-HSA-400206 R-HSA-1430728 R-HSA-1266738 |
Metabolism Developmental Biology |
R-HSA-1183003
(
R-HSA-381340
) R-HSA-1183058 ( R-HSA-381340 ) R-HSA-381309 ( R-HSA-381340 ) R-HSA-560472 ( R-HSA-381340 ) R-HSA-560473 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560491 ( R-HSA-381340 ) R-HSA-560493 ( R-HSA-381340 ) R-HSA-560498 ( R-HSA-381340 ) R-HSA-560510 ( R-HSA-381340 ) R-HSA-560517 ( R-HSA-1989781; R-HSA-381340 ) |
MONDO:0032897 | CDK8 | P49336 |
2.7.11.22 2.7.11.23 |
R-HSA-1989781 R-HSA-212436 R-HSA-381340 R-HSA-2122947 R-HSA-2173796 |
R-HSA-1980143 R-HSA-74160 R-HSA-400206 R-HSA-170834 R-HSA-157118 R-HSA-1430728 R-HSA-162582 R-HSA-9006936 R-HSA-556833 R-HSA-2173793 R-HSA-1266738 R-HSA-73857 |
Gene expression (Transcription) Metabolism Signal Transduction Developmental Biology |
R-HSA-1183003
(
R-HSA-381340
) R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1912391 ( R-HSA-2122947 ) R-HSA-1912393 ( R-HSA-2122947 ) R-HSA-212352 ( R-HSA-212436 ) R-HSA-212380 ( R-HSA-212436 ) R-HSA-212432 ( R-HSA-212436 ) R-HSA-2176475 ( R-HSA-212436; R-HSA-2173796 ) R-HSA-381309 ( R-HSA-381340 ) R-HSA-560472 ( R-HSA-381340 ) R-HSA-560473 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560491 ( R-HSA-381340 ) R-HSA-560493 ( R-HSA-381340 ) R-HSA-560498 ( R-HSA-381340 ) R-HSA-560510 ( R-HSA-381340 ) R-HSA-560517 ( R-HSA-1989781; R-HSA-381340 ) |
MONDO:0044302 | CDK13 | Q14004 |
2.7.11.22 2.7.11.23 |
R-HSA-6798695 R-HSA-6796648 |
R-HSA-3700989 R-HSA-212436 R-HSA-168256 R-HSA-168249 R-HSA-74160 R-HSA-73857 |
Immune System Gene expression (Transcription) |
R-HSA-6797100
(
R-HSA-6796648
) R-HSA-6800434 ( R-HSA-6798695 ) |
MONDO:0044324 | CDK10 | Q15131 | 2.7.11.22 |