DAR - Bologna Biocomputing Group

Search summary (EC number: 2.7.1.40)

Number of enzymes:	1
Number of disease:	2
Number of reactomes:	3
Number of reactions:	3

Search results (EC number: 2.7.1.40)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007067	PKLR	P30613	2.7.1.40	R-HSA-163765 R-HSA-163765 Reactome Name: ChREBP activates metabolic gene expression See in Reactome R-HSA-210745 R-HSA-210745 Reactome Name: Regulation of gene expression in beta cells See in Reactome R-HSA-70171 R-HSA-70171 Reactome Name: Glycolysis See in Reactome	R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-163685 R-HSA-163685 Reactome Name: Integration of energy metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-186712 R-HSA-186712 Reactome Name: Regulation of beta-cell development See in Reactome	Metabolism Developmental Biology	R-HSA-163669 ( R-HSA-163765 ) R-HSA-163669 Reaction Name: Transcriptional activation of pyruvate kinase gene by ChREBP:MLX See in Reactome R-HSA-211461 ( R-HSA-210745 ) R-HSA-211461 Reaction Name: HNF1A-dependent synthesis of the L isoform of PKLR protein See in Reactome R-HSA-71670 ( R-HSA-70171 ) R-HSA-71670 Reaction Name: phosphoenolpyruvate + ADP => pyruvate + ATP See in Reactome
MONDO:0009950	PKLR	P30613	2.7.1.40	R-HSA-163765 R-HSA-163765 Reactome Name: ChREBP activates metabolic gene expression See in Reactome R-HSA-210745 R-HSA-210745 Reactome Name: Regulation of gene expression in beta cells See in Reactome R-HSA-70171 R-HSA-70171 Reactome Name: Glycolysis See in Reactome	R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-163685 R-HSA-163685 Reactome Name: Integration of energy metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-186712 R-HSA-186712 Reactome Name: Regulation of beta-cell development See in Reactome	Metabolism Developmental Biology	R-HSA-163669 ( R-HSA-163765 ) R-HSA-163669 Reaction Name: Transcriptional activation of pyruvate kinase gene by ChREBP:MLX See in Reactome R-HSA-211461 ( R-HSA-210745 ) R-HSA-211461 Reaction Name: HNF1A-dependent synthesis of the L isoform of PKLR protein See in Reactome R-HSA-71670 ( R-HSA-70171 ) R-HSA-71670 Reaction Name: phosphoenolpyruvate + ADP => pyruvate + ATP See in Reactome