DAR - Bologna Biocomputing Group

Search summary (EC number: 2.4.1.50)

Number of enzymes:	2
Number of disease:	2
Number of reactomes:	1
Number of reactions:	10

Search results (EC number: 2.4.1.50)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0012892	PLOD3	O60568	1.14.11.4 2.4.1.66 2.4.1.50	R-HSA-1650814 R-HSA-1650814 Reactome Name: Collagen biosynthesis and modifying enzymes See in Reactome	R-HSA-1474244 R-HSA-1474244 Reactome Name: Extracellular matrix organization See in Reactome R-HSA-1474290 R-HSA-1474290 Reactome Name: Collagen formation See in Reactome	Extracellular matrix organization	R-HSA-1981104 ( R-HSA-1650814 ) R-HSA-1981104 Reaction Name: Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines See in Reactome R-HSA-1981128 ( R-HSA-1650814 ) R-HSA-1981128 Reaction Name: Galactosylation of collagen propeptide hydroxylysines by PLOD3 See in Reactome R-HSA-1981157 ( R-HSA-1650814 ) R-HSA-1981157 Reaction Name: Glucosylation of collagen propeptide hydroxylysines See in Reactome R-HSA-8948219 ( R-HSA-1650814 ) R-HSA-8948219 Reaction Name: PLOD3 binds Lysyl hydroxylated collagen propeptides See in Reactome R-HSA-8948222 ( R-HSA-1650814 ) R-HSA-8948222 Reaction Name: PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates See in Reactome R-HSA-8948224 ( R-HSA-1650814 ) R-HSA-8948224 Reaction Name: PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates See in Reactome R-HSA-8948232 ( R-HSA-1650814 ) R-HSA-8948232 Reaction Name: Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases See in Reactome
MONDO:0100105	COLGALT1	Q8NBJ5	2.4.1.50	R-HSA-1650814 R-HSA-1650814 Reactome Name: Collagen biosynthesis and modifying enzymes See in Reactome	R-HSA-1474244 R-HSA-1474244 Reactome Name: Extracellular matrix organization See in Reactome R-HSA-1474290 R-HSA-1474290 Reactome Name: Collagen formation See in Reactome	Extracellular matrix organization	R-HSA-1981120 ( R-HSA-1650814 ) R-HSA-1981120 Reaction Name: Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. See in Reactome R-HSA-8948228 ( R-HSA-1650814 ) R-HSA-8948228 Reaction Name: COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides See in Reactome R-HSA-8948231 ( R-HSA-1650814 ) R-HSA-8948231 Reaction Name: COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates See in Reactome