DAR - Bologna Biocomputing Group

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0010703	OTC	P00480	2.1.3.3	R-HSA-1268020 R-HSA-1268020 Reactome Name: Mitochondrial protein import See in Reactome R-HSA-70635 R-HSA-70635 Reactome Name: Urea cycle See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-9609507 R-HSA-9609507 Reactome Name: Protein localization See in Reactome	Metabolism Protein localization	R-HSA-1299475 ( R-HSA-1268020 ) R-HSA-1299475 Reaction Name: TIMM23 PAM translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix See in Reactome R-HSA-1299478 ( R-HSA-1268020 ) R-HSA-1299478 Reaction Name: MPP cleaves targeting peptide (presequence) of matrix precursors See in Reactome R-HSA-1299480 ( R-HSA-1268020 ) R-HSA-1299480 Reaction Name: Precursor proteins enter TIMM23 PAM See in Reactome R-HSA-70560 ( R-HSA-70635 ) R-HSA-70560 Reaction Name: carbamoyl phosphate + ornithine => citrulline + orthophosphate See in Reactome R-HSA-8986181 ( R-HSA-1268020 ) R-HSA-8986181 Reaction Name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) See in Reactome