DAR - Bologna Biocomputing Group

Search summary (EC number: 2.1.1.13)

Number of enzymes:	1
Number of disease:	2
Number of reactomes:	4
Number of reactions:	5

Search results (EC number: 2.1.1.13)

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DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0009609	MTR	Q99707	2.1.1.13	R-HSA-9013407 R-HSA-9013407 Reactome Name: RHOH GTPase cycle See in Reactome R-HSA-1614635 R-HSA-1614635 Reactome Name: Sulfur amino acid metabolism See in Reactome R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome R-HSA-156581 R-HSA-156581 Reactome Name: Methylation See in Reactome	R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-156580 R-HSA-156580 Reactome Name: Phase II - Conjugation of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Metabolism Signal Transduction	R-HSA-174374 ( R-HSA-156581; R-HSA-1614635; R-HSA-196741 ) R-HSA-174374 Reaction Name: MTR transfers CH3 from MeCbl to HCYS See in Reactome R-HSA-3149518 ( R-HSA-196741 ) R-HSA-3149518 Reaction Name: MTRR reduces cob(II)alamin to meCbl See in Reactome R-HSA-3149539 ( R-HSA-196741 ) R-HSA-3149539 Reaction Name: MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin See in Reactome R-HSA-3204318 ( R-HSA-196741 ) R-HSA-3204318 Reaction Name: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR See in Reactome R-HSA-9018758 ( R-HSA-9013407 ) R-HSA-9018758 Reaction Name: RHOH binds effectors at the plasma membrane See in Reactome
MONDO:0011120	MTR	Q99707	2.1.1.13	R-HSA-9013407 R-HSA-9013407 Reactome Name: RHOH GTPase cycle See in Reactome R-HSA-1614635 R-HSA-1614635 Reactome Name: Sulfur amino acid metabolism See in Reactome R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome R-HSA-156581 R-HSA-156581 Reactome Name: Methylation See in Reactome	R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-156580 R-HSA-156580 Reactome Name: Phase II - Conjugation of compounds See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Metabolism Signal Transduction	R-HSA-174374 ( R-HSA-156581; R-HSA-1614635; R-HSA-196741 ) R-HSA-174374 Reaction Name: MTR transfers CH3 from MeCbl to HCYS See in Reactome R-HSA-3149518 ( R-HSA-196741 ) R-HSA-3149518 Reaction Name: MTRR reduces cob(II)alamin to meCbl See in Reactome R-HSA-3149539 ( R-HSA-196741 ) R-HSA-3149539 Reaction Name: MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin See in Reactome R-HSA-3204318 ( R-HSA-196741 ) R-HSA-3204318 Reaction Name: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR See in Reactome R-HSA-9018758 ( R-HSA-9013407 ) R-HSA-9018758 Reaction Name: RHOH binds effectors at the plasma membrane See in Reactome

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