DAR - Bologna Biocomputing Group

Search summary (EC number: 1.4.1.3)

Number of enzymes:	1
Number of disease:	2
Number of reactomes:	2
Number of reactions:	4

Search results (EC number: 1.4.1.3)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0009734	GLUD1	P00367	1.4.1.3	R-HSA-8964539 R-HSA-8964539 Reactome Name: Glutamate and glutamine metabolism See in Reactome R-HSA-2151201 R-HSA-2151201 Reactome Name: Transcriptional activation of mitochondrial biogenesis See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1852241 R-HSA-1852241 Reactome Name: Organelle biogenesis and maintenance See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1592230 R-HSA-1592230 Reactome Name: Mitochondrial biogenesis See in Reactome	Organelle biogenesis and maintenance Metabolism	R-HSA-5688276 ( R-HSA-2151201 ) R-HSA-5688276 Reaction Name: SIRT4 transfers ADPRib to GLUD See in Reactome R-HSA-5688289 ( R-HSA-2151201 ) R-HSA-5688289 Reaction Name: SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 See in Reactome R-HSA-70589 ( R-HSA-8964539 ) R-HSA-70589 Reaction Name: alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] See in Reactome R-HSA-70600 ( R-HSA-8964539 ) R-HSA-70600 Reaction Name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] See in Reactome
MONDO:0011717	GLUD1	P00367	1.4.1.3	R-HSA-8964539 R-HSA-8964539 Reactome Name: Glutamate and glutamine metabolism See in Reactome R-HSA-2151201 R-HSA-2151201 Reactome Name: Transcriptional activation of mitochondrial biogenesis See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1852241 R-HSA-1852241 Reactome Name: Organelle biogenesis and maintenance See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1592230 R-HSA-1592230 Reactome Name: Mitochondrial biogenesis See in Reactome	Organelle biogenesis and maintenance Metabolism	R-HSA-5688276 ( R-HSA-2151201 ) R-HSA-5688276 Reaction Name: SIRT4 transfers ADPRib to GLUD See in Reactome R-HSA-5688289 ( R-HSA-2151201 ) R-HSA-5688289 Reaction Name: SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 See in Reactome R-HSA-70589 ( R-HSA-8964539 ) R-HSA-70589 Reaction Name: alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] See in Reactome R-HSA-70600 ( R-HSA-8964539 ) R-HSA-70600 Reaction Name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] See in Reactome