DAR - Bologna Biocomputing Group

Search summary (EC number: 1.17.4.1)

Number of enzymes:	1
Number of disease:	5
Number of reactomes:	2
Number of reactions:	3

Search results (EC number: 1.17.4.1)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0010787	RRM2B	Q7LG56	1.17.4.1	R-HSA-499943 R-HSA-499943 Reactome Name: Interconversion of nucleotide di- and triphosphates See in Reactome R-HSA-5628897 R-HSA-5628897 Reactome Name: TP53 Regulates Metabolic Genes See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism	R-HSA-111804 ( R-HSA-499943 ) R-HSA-111804 Reaction Name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) See in Reactome R-HSA-5632892 ( R-HSA-5628897 ) R-HSA-5632892 Reaction Name: TP53 stimulates transcription of RRM2B gene See in Reactome R-HSA-8866405 ( R-HSA-499943 ) R-HSA-8866405 Reaction Name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) See in Reactome
MONDO:0012792	RRM2B	Q7LG56	1.17.4.1	R-HSA-499943 R-HSA-499943 Reactome Name: Interconversion of nucleotide di- and triphosphates See in Reactome R-HSA-5628897 R-HSA-5628897 Reactome Name: TP53 Regulates Metabolic Genes See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism	R-HSA-111804 ( R-HSA-499943 ) R-HSA-111804 Reaction Name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) See in Reactome R-HSA-5632892 ( R-HSA-5628897 ) R-HSA-5632892 Reaction Name: TP53 stimulates transcription of RRM2B gene See in Reactome R-HSA-8866405 ( R-HSA-499943 ) R-HSA-8866405 Reaction Name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) See in Reactome
MONDO:0013117	RRM2B	Q7LG56	1.17.4.1	R-HSA-499943 R-HSA-499943 Reactome Name: Interconversion of nucleotide di- and triphosphates See in Reactome R-HSA-5628897 R-HSA-5628897 Reactome Name: TP53 Regulates Metabolic Genes See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism	R-HSA-111804 ( R-HSA-499943 ) R-HSA-111804 Reaction Name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) See in Reactome R-HSA-5632892 ( R-HSA-5628897 ) R-HSA-5632892 Reaction Name: TP53 stimulates transcription of RRM2B gene See in Reactome R-HSA-8866405 ( R-HSA-499943 ) R-HSA-8866405 Reaction Name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) See in Reactome
MONDO:0017575	RRM2B	Q7LG56	1.17.4.1	R-HSA-499943 R-HSA-499943 Reactome Name: Interconversion of nucleotide di- and triphosphates See in Reactome R-HSA-5628897 R-HSA-5628897 Reactome Name: TP53 Regulates Metabolic Genes See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism	R-HSA-111804 ( R-HSA-499943 ) R-HSA-111804 Reaction Name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) See in Reactome R-HSA-5632892 ( R-HSA-5628897 ) R-HSA-5632892 Reaction Name: TP53 stimulates transcription of RRM2B gene See in Reactome R-HSA-8866405 ( R-HSA-499943 ) R-HSA-8866405 Reaction Name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) See in Reactome
MONDO:0018002	RRM2B	Q7LG56	1.17.4.1	R-HSA-499943 R-HSA-499943 Reactome Name: Interconversion of nucleotide di- and triphosphates See in Reactome R-HSA-5628897 R-HSA-5628897 Reactome Name: TP53 Regulates Metabolic Genes See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism	R-HSA-111804 ( R-HSA-499943 ) R-HSA-111804 Reaction Name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) See in Reactome R-HSA-5632892 ( R-HSA-5628897 ) R-HSA-5632892 Reaction Name: TP53 stimulates transcription of RRM2B gene See in Reactome R-HSA-8866405 ( R-HSA-499943 ) R-HSA-8866405 Reaction Name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) See in Reactome