MONDO:0001071 |
MONDO:0001071
Disease Name: intellectual disability
Orphanet id: Orphanet:319658
All associated enzymes in DAR:
CYP2U1
DHX16
CBS
POLG
UFSP2
P4HTM
PDIA3
DHX30
TET3
ALG3
NAGLU
CHD3
SMPD1
DHX34
GCH1
CARNMT1
CYP27A1
ABCD1
CHD2
DDX54
INO80
PTPN4
DHX37
CYP2U1 |
Q7Z449 |
1.14.14.80
|
R-HSA-2142816
R-HSA-2142816
Reactome Name: Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
See in Reactome
R-HSA-211958
|
R-HSA-211897
R-HSA-211897
Reactome Name: Cytochrome P450 - arranged by substrate type
See in Reactome
R-HSA-211859
R-HSA-211945
R-HSA-211945
Reactome Name: Phase I - Functionalization of compounds
See in Reactome
R-HSA-1430728
R-HSA-8978868
R-HSA-2142753
R-HSA-556833
|
Metabolism
|
R-HSA-211960
(
R-HSA-211958
)
R-HSA-2161814
(
R-HSA-2142816
)
R-HSA-2161814
Reaction Name: Arachidonic acid is hydroxylated to 19-HETE by CYP(2)
See in Reactome
R-HSA-2161940
(
R-HSA-2142816
)
R-HSA-2161940
Reaction Name: Arachidonic acid is hydroxylated to 20-HETE by CYP(3)
See in Reactome
|
MONDO:0008865 |
CYP4V2 |
Q6ZWL3 |
1.14.14.79
1.14.14.80
|
R-HSA-211976
R-HSA-2453902
R-HSA-2453902
Reactome Name: The canonical retinoid cycle in rods (twilight vision)
See in Reactome
|
R-HSA-211897
R-HSA-211897
Reactome Name: Cytochrome P450 - arranged by substrate type
See in Reactome
R-HSA-2187338
R-HSA-211859
R-HSA-9709957
R-HSA-211945
R-HSA-211945
Reactome Name: Phase I - Functionalization of compounds
See in Reactome
R-HSA-1430728
|
Sensory Perception
Metabolism
|
R-HSA-6786239
(
R-HSA-211976;
R-HSA-2453902
)
R-HSA-6786239
Reaction Name: CYP4V2 omega-hydroxylates DHA to HDoHE
See in Reactome
|
MONDO:0014015 |
CYP2U1 |
Q7Z449 |
1.14.14.80
|
R-HSA-2142816
R-HSA-2142816
Reactome Name: Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
See in Reactome
R-HSA-211958
|
R-HSA-211897
R-HSA-211897
Reactome Name: Cytochrome P450 - arranged by substrate type
See in Reactome
R-HSA-211859
R-HSA-211945
R-HSA-211945
Reactome Name: Phase I - Functionalization of compounds
See in Reactome
R-HSA-1430728
R-HSA-8978868
R-HSA-2142753
R-HSA-556833
|
Metabolism
|
R-HSA-211960
(
R-HSA-211958
)
R-HSA-2161814
(
R-HSA-2142816
)
R-HSA-2161814
Reaction Name: Arachidonic acid is hydroxylated to 19-HETE by CYP(2)
See in Reactome
R-HSA-2161940
(
R-HSA-2142816
)
R-HSA-2161940
Reaction Name: Arachidonic acid is hydroxylated to 20-HETE by CYP(3)
See in Reactome
|
MONDO:0019200 |
CYP4V2 |
Q6ZWL3 |
1.14.14.79
1.14.14.80
|
R-HSA-211976
R-HSA-2453902
R-HSA-2453902
Reactome Name: The canonical retinoid cycle in rods (twilight vision)
See in Reactome
|
R-HSA-211897
R-HSA-211897
Reactome Name: Cytochrome P450 - arranged by substrate type
See in Reactome
R-HSA-2187338
R-HSA-211859
R-HSA-9709957
R-HSA-211945
R-HSA-211945
Reactome Name: Phase I - Functionalization of compounds
See in Reactome
R-HSA-1430728
|
Sensory Perception
Metabolism
|
R-HSA-6786239
(
R-HSA-211976;
R-HSA-2453902
)
R-HSA-6786239
Reaction Name: CYP4V2 omega-hydroxylates DHA to HDoHE
See in Reactome
|