DAR - Bologna Biocomputing Group

Search summary (EC number: 1.14.11.67)

Number of enzymes:	2
Number of disease:	2
Number of reactomes:	2
Number of reactions:	5

Search results (EC number: 1.14.11.67)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0010355	KDM5C	P41229	1.14.11.67	R-HSA-3214842 R-HSA-3214842 Reactome Name: HDMs demethylate histones See in Reactome	R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome	Chromatin organization	R-HSA-4754181 ( R-HSA-3214842 ) R-HSA-4754181 Reaction Name: KDM5A-D demethylate Me2K5-histone H3 See in Reactome R-HSA-5661116 ( R-HSA-3214842 ) R-HSA-5661116 Reaction Name: KDM5A-D demethylate Me3K5-histone H3 See in Reactome
MONDO:0020850	KDM5B	Q9UGL1	1.14.11.67	R-HSA-8866911 R-HSA-8866911 Reactome Name: TFAP2 (AP-2) family regulates transcription of cell cycle factors See in Reactome R-HSA-3214842 R-HSA-3214842 Reactome Name: HDMs demethylate histones See in Reactome	R-HSA-8864260 R-HSA-8864260 Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome	Gene expression (Transcription) Chromatin organization	R-HSA-4754181 ( R-HSA-3214842 ) R-HSA-4754181 Reaction Name: KDM5A-D demethylate Me2K5-histone H3 See in Reactome R-HSA-5661116 ( R-HSA-3214842 ) R-HSA-5661116 Reaction Name: KDM5A-D demethylate Me3K5-histone H3 See in Reactome R-HSA-8865256 ( R-HSA-8866911 ) R-HSA-8865256 Reaction Name: CDKN1A gene expression is stimulated by TFAP2A and repressed by TFAP2C See in Reactome R-HSA-8865265 ( R-HSA-8866911 ) R-HSA-8865265 Reaction Name: TFAP2C homodimer binds MYC and KDM5B See in Reactome R-HSA-8865280 ( R-HSA-8866911 ) R-HSA-8865280 Reaction Name: TFAP2C homodimer binds the CDKN1A (p21) gene promoter See in Reactome