DAR - Bologna Biocomputing Group

Search summary (EC number: 1.14.11.65)

Number of enzymes:	3
Number of disease:	5
Number of reactomes:	2
Number of reactions:	3

Search results (EC number: 1.14.11.65)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007806	HR	O43593	1.14.11.65
MONDO:0008757	HR	O43593	1.14.11.65
MONDO:0008847	HR	O43593	1.14.11.65
MONDO:0010286	PHF8	Q9UPP1	1.14.11.65 1.14.11.27	R-HSA-2299718 R-HSA-2299718 Reactome Name: Condensation of Prophase Chromosomes See in Reactome R-HSA-3214842 R-HSA-3214842 Reactome Name: HDMs demethylate histones See in Reactome	R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome R-HSA-68875 R-HSA-68875 Reactome Name: Mitotic Prophase See in Reactome	Chromatin organization Cell Cycle	R-HSA-4724284 ( R-HSA-3214842 ) R-HSA-4724284 Reaction Name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 See in Reactome R-HSA-5423117 ( R-HSA-3214842 ) R-HSA-5423117 Reaction Name: PHF8 demethylates MeK21-histone H4 See in Reactome R-HSA-5661115 ( R-HSA-3214842 ) R-HSA-5661115 Reaction Name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 See in Reactome
MONDO:0030012	KDM3B	Q7LBC6	1.14.11.65	R-HSA-3214842 R-HSA-3214842 Reactome Name: HDMs demethylate histones See in Reactome	R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome	Chromatin organization	R-HSA-4724284 ( R-HSA-3214842 ) R-HSA-4724284 Reaction Name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 See in Reactome R-HSA-5661115 ( R-HSA-3214842 ) R-HSA-5661115 Reaction Name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 See in Reactome