DAR - Bologna Biocomputing Group

Search summary (EC number: 1.1.1.37)

Number of enzymes:	3
Number of disease:	5
Number of reactomes:	3
Number of reactions:	4

Search results (EC number: 1.1.1.37)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0009736	PHGDH	O43175	1.1.1.399 1.1.1.95 1.1.1.37	R-HSA-977347 R-HSA-977347 Reactome Name: Serine biosynthesis See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-977348 ( R-HSA-977347 ) R-HSA-977348 Reaction Name: PHGDH tetramer dehydrogenates 3PG See in Reactome
MONDO:0011152	PHGDH	O43175	1.1.1.399 1.1.1.95 1.1.1.37	R-HSA-977347 R-HSA-977347 Reactome Name: Serine biosynthesis See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-977348 ( R-HSA-977347 ) R-HSA-977348 Reaction Name: PHGDH tetramer dehydrogenates 3PG See in Reactome
MONDO:0015025	MDH2	P40926	1.1.1.37	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-71403 R-HSA-71403 Reactome Name: Citric acid cycle (TCA cycle) See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-71406 R-HSA-71406 Reactome Name: Pyruvate metabolism and Citric Acid (TCA) cycle See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-70979 ( R-HSA-71403 ) R-HSA-70979 Reaction Name: (S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ See in Reactome R-HSA-71783 ( R-HSA-70263; R-HSA-71403 ) R-HSA-71783 Reaction Name: Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+ See in Reactome
MONDO:0017366	MDH2	P40926	1.1.1.37	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-71403 R-HSA-71403 Reactome Name: Citric acid cycle (TCA cycle) See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-71406 R-HSA-71406 Reactome Name: Pyruvate metabolism and Citric Acid (TCA) cycle See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-70979 ( R-HSA-71403 ) R-HSA-70979 Reaction Name: (S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ See in Reactome R-HSA-71783 ( R-HSA-70263; R-HSA-71403 ) R-HSA-71783 Reaction Name: Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+ See in Reactome
MONDO:0030072	MDH1	P40925	1.1.1.96 1.1.1.37	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-198508 ( R-HSA-70263 ) R-HSA-198508 Reaction Name: malate + NAD+ <=> oxaloacetate + NADH + H+ See in Reactome