DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0060666)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	3
Number of reactions:	6

Search results (Disease ID: MONDO:0060666)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0060666	CTBP1	Q13363	1.1.1.-	R-HSA-3899300 R-HSA-3899300 Reactome Name: SUMOylation of transcription cofactors See in Reactome R-HSA-3769402 R-HSA-3769402 Reactome Name: Deactivation of the beta-catenin transactivating complex See in Reactome R-HSA-4641265 R-HSA-4641265 Reactome Name: Repression of WNT target genes See in Reactome	R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-195253 R-HSA-195253 Reactome Name: Degradation of beta-catenin by the destruction complex See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Metabolism of proteins Signal Transduction	R-HSA-3108203 ( R-HSA-3899300 ) R-HSA-3108203 Reaction Name: PRC1 SUMOylates CTBP1 with SUMO2,3 See in Reactome R-HSA-3108209 ( R-HSA-3899300 ) R-HSA-3108209 Reaction Name: PRC1 SUMOylates CTBP1 with SUMO1 See in Reactome R-HSA-3361751 ( R-HSA-3769402 ) R-HSA-3361751 Reaction Name: beta-catenin is replaced by repression complexes at the promoter See in Reactome R-HSA-3364042 ( R-HSA-3769402 ) R-HSA-3364042 Reaction Name: APC promotes disassembly of beta-catenin transactivation complex See in Reactome R-HSA-5229348 ( R-HSA-4641265 ) R-HSA-5229348 Reaction Name: Transcription of canonical WNT targets is repressed by the TLE:HDAC and TCF/CTBP complexes See in Reactome R-HSA-5334050 ( R-HSA-4641265 ) R-HSA-5334050 Reaction Name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes See in Reactome