DAR - Bologna Biocomputing Group

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0019087	PTPN3	P26045	3.1.3.48	R-HSA-5675221 R-HSA-5675221 Reactome Name: Negative regulation of MAPK pathway See in Reactome R-HSA-182971 R-HSA-182971 Reactome Name: EGFR downregulation See in Reactome	R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-5684996 R-HSA-5684996 Reactome Name: MAPK1/MAPK3 signaling See in Reactome R-HSA-177929 R-HSA-177929 Reactome Name: Signaling by EGFR See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-5673001 R-HSA-5673001 Reactome Name: RAF/MAP kinase cascade See in Reactome	Signal Transduction	R-HSA-8867047 ( R-HSA-182971 ) R-HSA-8867047 Reaction Name: PTPN3 dephosphorylates EPS15 See in Reactome R-HSA-8867654 ( R-HSA-5675221 ) R-HSA-8867654 Reaction Name: PTPN3 binds p-T183,Y185 MAPK12 See in Reactome R-HSA-8867658 ( R-HSA-5675221 ) R-HSA-8867658 Reaction Name: PTPN3 dephosphorylates MAPK12 See in Reactome R-HSA-8868118 ( R-HSA-5675221 ) R-HSA-8868118 Reaction Name: MAPK12 phosphorylates PTPN3 See in Reactome