DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0018881)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	4
Number of reactions:	6

Search results (Disease ID: MONDO:0018881)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0018881	DNMT3A	Q9Y6K1	2.1.1.37 2.1.1.-	R-HSA-3214858 R-HSA-3214858 Reactome Name: RMTs methylate histone arginines See in Reactome R-HSA-4655427 R-HSA-4655427 Reactome Name: SUMOylation of DNA methylation proteins See in Reactome R-HSA-212300 R-HSA-212300 Reactome Name: PRC2 methylates histones and DNA See in Reactome R-HSA-5334118 R-HSA-5334118 Reactome Name: DNA methylation See in Reactome	R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-3108232 R-HSA-3108232 Reactome Name: SUMO E3 ligases SUMOylate target proteins See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-2990846 R-HSA-2990846 Reactome Name: SUMOylation See in Reactome R-HSA-212165 R-HSA-212165 Reactome Name: Epigenetic regulation of gene expression See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome	Gene expression (Transcription) Metabolism of proteins Chromatin organization	R-HSA-212222 ( R-HSA-212300 ) R-HSA-212222 Reaction Name: PRC2 recruits DNA methyltransferases See in Reactome R-HSA-212269 ( R-HSA-212300 ) R-HSA-212269 Reaction Name: DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 See in Reactome R-HSA-4655440 ( R-HSA-4655427 ) R-HSA-4655440 Reaction Name: CBX4 (Pc2) SUMOylates DNMT3A with SUMO1 See in Reactome R-HSA-5212679 ( R-HSA-3214858 ) R-HSA-5212679 Reaction Name: DNMT3A binds Me2sR4-HIST1H4 See in Reactome R-HSA-5334152 ( R-HSA-5334118 ) R-HSA-5334152 Reaction Name: DNMT3A:DNMT3L methylates cytosine in DNA See in Reactome R-HSA-5334179 ( R-HSA-5334118 ) R-HSA-5334179 Reaction Name: DNMT3A:DNMT3L binds chromatin See in Reactome