DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0018614)

Number of enzymes:	8
Number of disease:	1
Number of reactomes:	29
Number of reactions:	91

Search results (Disease ID: MONDO:0018614)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0018614	SYNJ1	O43426	3.1.3.36	R-HSA-1660499 R-HSA-1660499 Reactome Name: Synthesis of PIPs at the plasma membrane See in Reactome R-HSA-1855183 R-HSA-1855183 Reactome Name: Synthesis of IP2, IP, and Ins in the cytosol See in Reactome R-HSA-8856828 R-HSA-8856828 Reactome Name: Clathrin-mediated endocytosis See in Reactome R-HSA-1855204 R-HSA-1855204 Reactome Name: Synthesis of IP3 and IP4 in the cytosol See in Reactome	R-HSA-1483249 R-HSA-1483249 Reactome Name: Inositol phosphate metabolism See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome R-HSA-1483255 R-HSA-1483255 Reactome Name: PI Metabolism See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome	Metabolism Vesicle-mediated transport	R-HSA-1675836 ( R-HSA-1660499 ) R-HSA-1675836 Reaction Name: PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane See in Reactome R-HSA-1675988 ( R-HSA-1660499 ) R-HSA-1675988 Reaction Name: PI4P is dephosphorylated to PI by SYNJ at the plasma membrane See in Reactome R-HSA-1675994 ( R-HSA-1660499 ) R-HSA-1675994 Reaction Name: PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane See in Reactome R-HSA-1676177 ( R-HSA-1660499 ) R-HSA-1676177 Reaction Name: PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane See in Reactome R-HSA-1676203 ( R-HSA-1660499 ) R-HSA-1676203 Reaction Name: PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane See in Reactome R-HSA-1855174 ( R-HSA-1855183 ) R-HSA-1855174 Reaction Name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol See in Reactome R-HSA-1855218 ( R-HSA-1855204 ) R-HSA-1855218 Reaction Name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol See in Reactome R-HSA-8868648 ( R-HSA-8856828 ) R-HSA-8868648 Reaction Name: SYNJ hydrolyze PI(4,5)P2 to PI(4)P See in Reactome R-HSA-8868651 ( R-HSA-8856828 ) R-HSA-8868651 Reaction Name: Endophilins recruit synaptojanins to the clathrin-coated pit See in Reactome R-HSA-8868658 ( R-HSA-8856828 ) R-HSA-8868658 Reaction Name: HSPA8-mediated ATP hydrolysis promotes vesicle uncoating See in Reactome R-HSA-8868659 ( R-HSA-8856828 ) R-HSA-8868659 Reaction Name: Clathrin recruits auxilins to the clathrin-coated vesicle See in Reactome R-HSA-8868660 ( R-HSA-8856828 ) R-HSA-8868660 Reaction Name: Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle See in Reactome R-HSA-8868661 ( R-HSA-8856828 ) R-HSA-8868661 Reaction Name: Dynamin-mediated GTP hydrolysis promotes vesicle scission See in Reactome R-HSA-8869438 ( R-HSA-8856828 ) R-HSA-8869438 Reaction Name: Dissociation of clathrin-associated proteins See in Reactome R-HSA-8871193 ( R-HSA-8856828 ) R-HSA-8871193 Reaction Name: Dissociation of AAK1 and dephosphorylation of AP-2 mu2 See in Reactome R-HSA-8871194 ( R-HSA-8856828 ) R-HSA-8871194 Reaction Name: RAB5 and GAPVD1 bind AP-2 See in Reactome
MONDO:0018614	CDK19	Q9BWU1	2.7.11.22	R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-381340 R-HSA-381340 Reactome Name: Transcriptional regulation of white adipocyte differentiation See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome	Metabolism Developmental Biology	R-HSA-1183003 ( R-HSA-381340 ) R-HSA-1183003 Reaction Name: Expression of Leptin See in Reactome R-HSA-1183058 ( R-HSA-381340 ) R-HSA-1183058 Reaction Name: Expression of Adiponectin See in Reactome R-HSA-381309 ( R-HSA-381340 ) R-HSA-381309 Reaction Name: PPARG:RXRA heterodimer binds to fatty acid-like ligands See in Reactome R-HSA-560472 ( R-HSA-381340 ) R-HSA-560472 Reaction Name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) See in Reactome R-HSA-560473 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560473 Reaction Name: Expression of ANGPTL4 See in Reactome R-HSA-560491 ( R-HSA-381340 ) R-HSA-560491 Reaction Name: Expression of CEBPA See in Reactome R-HSA-560493 ( R-HSA-381340 ) R-HSA-560493 Reaction Name: Expression of Perilipin (PLIN) See in Reactome R-HSA-560498 ( R-HSA-381340 ) R-HSA-560498 Reaction Name: Expression of Lipoprotein lipase (LPL) See in Reactome R-HSA-560510 ( R-HSA-381340 ) R-HSA-560510 Reaction Name: Expression of FABP4 (aP2) See in Reactome R-HSA-560517 ( R-HSA-1989781; R-HSA-381340 ) R-HSA-560517 Reaction Name: Expression of CD36 (platelet glycoprotein IV, FAT) See in Reactome
MONDO:0018614	ATP6V1A	P38606	7.1.2.2	R-HSA-1222556 R-HSA-1222556 Reactome Name: ROS and RNS production in phagocytes See in Reactome R-HSA-917977 R-HSA-917977 Reactome Name: Transferrin endocytosis and recycling See in Reactome R-HSA-983712 R-HSA-983712 Reactome Name: Ion channel transport See in Reactome R-HSA-9639288 R-HSA-9639288 Reactome Name: Amino acids regulate mTORC1 See in Reactome R-HSA-77387 R-HSA-77387 Reactome Name: Insulin receptor recycling See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-9711097 R-HSA-9711097 Reactome Name: Cellular response to starvation See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome R-HSA-917937 R-HSA-917937 Reactome Name: Iron uptake and transport See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-74752 R-HSA-74752 Reactome Name: Signaling by Insulin receptor See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Immune System Cellular responses to stimuli Transport of small molecules Signal Transduction	R-HSA-1222516 ( R-HSA-1222556 ) R-HSA-1222516 Reaction Name: Intraphagosomal pH is lowered to 5 by V-ATPase See in Reactome R-HSA-5252133 ( R-HSA-77387; R-HSA-917977; R-HSA-983712 ) R-HSA-5252133 Reaction Name: ATP6AP1 binds V-ATPase See in Reactome R-HSA-74723 ( R-HSA-77387 ) R-HSA-74723 Reaction Name: Endosome acidification See in Reactome R-HSA-917841 ( R-HSA-917977 ) R-HSA-917841 Reaction Name: Acidification of Tf:TfR1 containing endosome See in Reactome R-HSA-9639286 ( R-HSA-9639288 ) R-HSA-9639286 Reaction Name: RRAGC,D exchanges GTP for GDP See in Reactome R-HSA-9640167 ( R-HSA-9639288 ) R-HSA-9640167 Reaction Name: RRAGA,B exchanges GDP for GTP See in Reactome R-HSA-9640168 ( R-HSA-9639288 ) R-HSA-9640168 Reaction Name: v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine See in Reactome R-HSA-9640175 ( R-HSA-9639288 ) R-HSA-9640175 Reaction Name: v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine See in Reactome R-HSA-9640195 ( R-HSA-9639288 ) R-HSA-9640195 Reaction Name: RRAGA,B hydrolyzes GTP See in Reactome R-HSA-9645598 ( R-HSA-9639288 ) R-HSA-9645598 Reaction Name: RRAGC,D hydrolyzes GTP See in Reactome R-HSA-9645608 ( R-HSA-9639288 ) R-HSA-9645608 Reaction Name: v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 See in Reactome R-HSA-9646468 ( R-HSA-9639288 ) R-HSA-9646468 Reaction Name: mTORC1 binds RHEB:GTP See in Reactome
MONDO:0018614	PPP3CA	Q08209	3.1.3.16	R-HSA-2871809 R-HSA-2871809 Reactome Name: FCERI mediated Ca+2 mobilization See in Reactome R-HSA-4086398 R-HSA-4086398 Reactome Name: Ca2+ pathway See in Reactome R-HSA-180024 R-HSA-180024 Reactome Name: DARPP-32 events See in Reactome R-HSA-2025928 R-HSA-2025928 Reactome Name: Calcineurin activates NFAT See in Reactome R-HSA-5607763 R-HSA-5607763 Reactome Name: CLEC7A (Dectin-1) induces NFAT activation See in Reactome	R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-2454202 R-HSA-2454202 Reactome Name: Fc epsilon receptor (FCERI) signaling See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-3858494 R-HSA-3858494 Reactome Name: Beta-catenin independent WNT signaling See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-983705 R-HSA-983705 Reactome Name: Signaling by the B Cell Receptor (BCR) See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1168372 R-HSA-1168372 Reactome Name: Downstream signaling events of B Cell Receptor (BCR) See in Reactome R-HSA-5607764 R-HSA-5607764 Reactome Name: CLEC7A (Dectin-1) signaling See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Immune System Signal Transduction	R-HSA-201783 ( R-HSA-180024 ) R-HSA-201783 Reaction Name: Inactive catalytic PP2B is activated by the binding of calmodulin See in Reactome R-HSA-201787 ( R-HSA-180024 ) R-HSA-201787 Reaction Name: PPP3 complex dephosphorylates DARPP-32 on Thr34 See in Reactome R-HSA-2025882 ( R-HSA-2025928 ) R-HSA-2025882 Reaction Name: Calcineurin dephosphorylates NFATC1,2,3 See in Reactome R-HSA-2025890 ( R-HSA-2025928 ) R-HSA-2025890 Reaction Name: Calcineurin binds NFATC1,2,3 See in Reactome R-HSA-2730849 ( R-HSA-2871809; R-HSA-5607763 ) R-HSA-2730849 Reaction Name: Calcineurin binds and dephosphorylates NFAT See in Reactome R-HSA-2730867 ( R-HSA-2871809; R-HSA-5607763 ) R-HSA-2730867 Reaction Name: Translocation of CaN:CaM:NFAT to nucleus See in Reactome R-HSA-2730872 ( R-HSA-2871809; R-HSA-4086398; R-HSA-5607763 ) R-HSA-2730872 Reaction Name: Activation of Calcineurin See in Reactome R-HSA-4551451 ( R-HSA-4086398 ) R-HSA-4551451 Reaction Name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling See in Reactome R-HSA-4551465 ( R-HSA-4086398 ) R-HSA-4551465 Reaction Name: Translocation of NFATC1:CaN:CaM to nucleus See in Reactome
MONDO:0018614	NTRK2	Q16620	2.7.10.1	R-HSA-9032759 R-HSA-9032759 Reactome Name: NTRK2 activates RAC1 See in Reactome R-HSA-9032500 R-HSA-9032500 Reactome Name: Activated NTRK2 signals through FYN See in Reactome R-HSA-9024909 R-HSA-9024909 Reactome Name: BDNF activates NTRK2 (TRKB) signaling See in Reactome R-HSA-9026519 R-HSA-9026519 Reactome Name: Activated NTRK2 signals through RAS See in Reactome R-HSA-9025046 R-HSA-9025046 Reactome Name: NTF3 activates NTRK2 (TRKB) signaling See in Reactome R-HSA-9026527 R-HSA-9026527 Reactome Name: Activated NTRK2 signals through PLCG1 See in Reactome R-HSA-9028731 R-HSA-9028731 Reactome Name: Activated NTRK2 signals through FRS2 and FRS3 See in Reactome R-HSA-9032845 R-HSA-9032845 Reactome Name: Activated NTRK2 signals through CDK5 See in Reactome R-HSA-9028335 R-HSA-9028335 Reactome Name: Activated NTRK2 signals through PI3K See in Reactome R-HSA-9026357 R-HSA-9026357 Reactome Name: NTF4 activates NTRK2 (TRKB) signaling See in Reactome R-HSA-187024 R-HSA-187024 Reactome Name: NGF-independant TRKA activation See in Reactome	R-HSA-187015 R-HSA-187015 Reactome Name: Activation of TRKA receptors See in Reactome R-HSA-166520 R-HSA-166520 Reactome Name: Signaling by NTRKs See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-9006115 R-HSA-9006115 Reactome Name: Signaling by NTRK2 (TRKB) See in Reactome R-HSA-187037 R-HSA-187037 Reactome Name: Signaling by NTRK1 (TRKA) See in Reactome	Signal Transduction	R-HSA-187661 ( R-HSA-187024 ) R-HSA-187661 Reaction Name: Ade-Rib binds AODORA2A and NTRK1,2 See in Reactome R-HSA-187678 ( R-HSA-187024 ) R-HSA-187678 Reaction Name: ADCYAP1(2-742) binds ADCYAP1R1 and NTRK1,2 See in Reactome R-HSA-9024906 ( R-HSA-9024909 ) R-HSA-9024906 Reaction Name: BDNF binds NTRK2 (TRKB) See in Reactome R-HSA-9024967 ( R-HSA-9024909 ) R-HSA-9024967 Reaction Name: BDNF-bound NTRK2 dimerizes See in Reactome R-HSA-9025033 ( R-HSA-9025046 ) R-HSA-9025033 Reaction Name: NTF3 binds NTRK2 (TRKB) See in Reactome R-HSA-9026358 ( R-HSA-9026357 ) R-HSA-9026358 Reaction Name: NTF4 binds NTRK2 See in Reactome R-HSA-9026366 ( R-HSA-9025046 ) R-HSA-9026366 Reaction Name: NTF3-bound NTRK2 dimerizes See in Reactome R-HSA-9026377 ( R-HSA-9026357 ) R-HSA-9026377 Reaction Name: NTF4-bound NTRK2 dimerizes See in Reactome R-HSA-9026464 ( R-HSA-9024909 ) R-HSA-9026464 Reaction Name: BDNF-bound NTRK2 dimers trans-autophosphorylate See in Reactome R-HSA-9026493 ( R-HSA-9026519 ) R-HSA-9026493 Reaction Name: p-Y516 of p-5Y-NTRK2 recruits SHC1 See in Reactome R-HSA-9026502 ( R-HSA-9025046 ) R-HSA-9026502 Reaction Name: NTF3-bound NTRK2 dimers trans-autophosphorylate See in Reactome R-HSA-9026510 ( R-HSA-9026357 ) R-HSA-9026510 Reaction Name: NTF4-bound NTRK2 dimers trans-autophosphorylate See in Reactome R-HSA-9026531 ( R-HSA-9026527 ) R-HSA-9026531 Reaction Name: p-Y817 of p-5Y-NTRK2 recruits PLCG1 See in Reactome R-HSA-9026579 ( R-HSA-9026527 ) R-HSA-9026579 Reaction Name: NTRK2 phosphorylates PLCG1 See in Reactome R-HSA-9026890 ( R-HSA-9026519 ) R-HSA-9026890 Reaction Name: NTRK2 phosphorylates SHC1 See in Reactome R-HSA-9026891 ( R-HSA-9026519 ) R-HSA-9026891 Reaction Name: NTRK2 activates RAS signaling through SHC1 See in Reactome R-HSA-9026894 ( R-HSA-9026527 ) R-HSA-9026894 Reaction Name: Activated PCLG1 dissociates from NTRK2 See in Reactome R-HSA-9028328 ( R-HSA-9026519 ) R-HSA-9028328 Reaction Name: SHC1 bound to activated NTRK2 recruits GRB2:SOS1 See in Reactome R-HSA-9028505 ( R-HSA-9028335 ) R-HSA-9028505 Reaction Name: Activated NTRK2 recruits PI3K See in Reactome R-HSA-9028519 ( R-HSA-9028335 ) R-HSA-9028519 Reaction Name: NTRK2-activated PI3K generates PIP3 See in Reactome R-HSA-9028728 ( R-HSA-9028731 ) R-HSA-9028728 Reaction Name: NTRK2 phosphorylates FRS2 See in Reactome R-HSA-9028730 ( R-HSA-9028731 ) R-HSA-9028730 Reaction Name: Activated NTRK2 binds FRS2 See in Reactome R-HSA-9031981 ( R-HSA-9028731 ) R-HSA-9031981 Reaction Name: NTRK2-phosphorylated FRS2 binds PTPN11 See in Reactome R-HSA-9032067 ( R-HSA-9028731 ) R-HSA-9032067 Reaction Name: NTRK2 activates RAS signaling through FRS2 See in Reactome R-HSA-9032073 ( R-HSA-9028731 ) R-HSA-9032073 Reaction Name: NTRK2-phosphorylated FRS2 binds GRB2 See in Reactome R-HSA-9032402 ( R-HSA-9028731 ) R-HSA-9032402 Reaction Name: Activated NTRK2 binds FRS3 See in Reactome R-HSA-9032426 ( R-HSA-9028731 ) R-HSA-9032426 Reaction Name: NTRK2 phosphorylates FRS3 See in Reactome R-HSA-9032502 ( R-HSA-9032500 ) R-HSA-9032502 Reaction Name: Activated NTRK2 binds FYN See in Reactome R-HSA-9032532 ( R-HSA-9032500 ) R-HSA-9032532 Reaction Name: NTRK2-bound FYN autophosphorylates See in Reactome R-HSA-9032582 ( R-HSA-9032500 ) R-HSA-9032582 Reaction Name: Activated FYN binds GRIN2B See in Reactome R-HSA-9032601 ( R-HSA-9032500 ) R-HSA-9032601 Reaction Name: FYN-mediated phosphorylation of GRIN2B See in Reactome R-HSA-9032761 ( R-HSA-9032500; R-HSA-9032759 ) R-HSA-9032761 Reaction Name: DOCK3 binds FYN associated with NTRK2 See in Reactome R-HSA-9032798 ( R-HSA-9032500; R-HSA-9032759 ) R-HSA-9032798 Reaction Name: DOCK3 activates RAC1 See in Reactome R-HSA-9032841 ( R-HSA-9032845 ) R-HSA-9032841 Reaction Name: Activated NTRK2 binds CDK5 See in Reactome R-HSA-9032854 ( R-HSA-9032845 ) R-HSA-9032854 Reaction Name: NTRK2 phosphorylates CDK5 See in Reactome R-HSA-9032863 ( R-HSA-9032845 ) R-HSA-9032863 Reaction Name: CDK5 phosphorylates NTRK2 See in Reactome R-HSA-9033276 ( R-HSA-9032845 ) R-HSA-9033276 Reaction Name: NTRK2 binds TIAM1 See in Reactome R-HSA-9033284 ( R-HSA-9032845 ) R-HSA-9033284 Reaction Name: NTRK2 promotes TIAM1 phosphorylation See in Reactome R-HSA-9033292 ( R-HSA-9032845 ) R-HSA-9033292 Reaction Name: NTRK2 and CDK5 promote activation of RAC1 by TIAM1 See in Reactome R-HSA-9037040 ( R-HSA-9032500 ) R-HSA-9037040 Reaction Name: SRC,FYN phosphorylate NTRK2 See in Reactome R-HSA-9612996 ( R-HSA-187024 ) R-HSA-9612996 Reaction Name: NTRK1,2 in ADCYAP1(2-742):ADCYAP1R1:NTRK1,2 autophosphorylates See in Reactome R-HSA-9613023 ( R-HSA-187024 ) R-HSA-9613023 Reaction Name: NTRK1,2 in Ade-Rib:ADORA2A:NTRK1,2 autophosphorylates See in Reactome
MONDO:0018614	DHDDS	Q86SQ9	2.5.1.87	R-HSA-446199 R-HSA-446199 Reactome Name: Synthesis of Dolichyl-phosphate See in Reactome	R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-446219 R-HSA-446219 Reactome Name: Synthesis of substrates in N-glycan biosythesis See in Reactome R-HSA-446193 R-HSA-446193 Reactome Name: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Metabolism of proteins	R-HSA-4419978 ( R-HSA-446199 ) R-HSA-4419978 Reaction Name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP See in Reactome
MONDO:0018614	PARS2	Q7L3T8	6.1.1.15	R-HSA-379726 R-HSA-379726 Reactome Name: Mitochondrial tRNA aminoacylation See in Reactome	R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-379724 R-HSA-379724 Reactome Name: tRNA Aminoacylation See in Reactome R-HSA-72766 R-HSA-72766 Reactome Name: Translation See in Reactome	Metabolism of proteins	R-HSA-380198 ( R-HSA-379726 ) R-HSA-380198 Reaction Name: proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate See in Reactome
MONDO:0018614	NUS1	Q96E22	2.5.1.87	R-HSA-446199 R-HSA-446199 Reactome Name: Synthesis of Dolichyl-phosphate See in Reactome	R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-446219 R-HSA-446219 Reactome Name: Synthesis of substrates in N-glycan biosythesis See in Reactome R-HSA-446193 R-HSA-446193 Reactome Name: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Metabolism of proteins	R-HSA-4419978 ( R-HSA-446199 ) R-HSA-4419978 Reaction Name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP See in Reactome