DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0017366)

Number of enzymes:	3
Number of disease:	1
Number of reactomes:	4
Number of reactions:	7

Search results (Disease ID: MONDO:0017366)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0017366	MDH2	P40926	1.1.1.37	R-HSA-70263 R-HSA-70263 Reactome Name: Gluconeogenesis See in Reactome R-HSA-71403 R-HSA-71403 Reactome Name: Citric acid cycle (TCA cycle) See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-71406 R-HSA-71406 Reactome Name: Pyruvate metabolism and Citric Acid (TCA) cycle See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome	Metabolism	R-HSA-70979 ( R-HSA-71403 ) R-HSA-70979 Reaction Name: (S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ See in Reactome R-HSA-71783 ( R-HSA-70263; R-HSA-71403 ) R-HSA-71783 Reaction Name: Oxaloacetate + NADH + H+ <=> (S)-Malate + NAD+ See in Reactome
MONDO:0017366	FH	P07954	4.2.1.2	R-HSA-71403 R-HSA-71403 Reactome Name: Citric acid cycle (TCA cycle) See in Reactome	R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome R-HSA-71406 R-HSA-71406 Reactome Name: Pyruvate metabolism and Citric Acid (TCA) cycle See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-451033 ( R-HSA-71403 ) R-HSA-451033 Reaction Name: (S)-Malate <=> Fumarate + H2O See in Reactome R-HSA-70982 ( R-HSA-71403 ) R-HSA-70982 Reaction Name: Fumarate + H2O <=> (S)-Malate See in Reactome
MONDO:0017366	DLST	P36957	2.3.1.61	R-HSA-389661 R-HSA-389661 Reactome Name: Glyoxylate metabolism and glycine degradation See in Reactome R-HSA-71403 R-HSA-71403 Reactome Name: Citric acid cycle (TCA cycle) See in Reactome R-HSA-71064 R-HSA-71064 Reactome Name: Lysine catabolism See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-71406 R-HSA-71406 Reactome Name: Pyruvate metabolism and Citric Acid (TCA) cycle See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-1428517 R-HSA-1428517 Reactome Name: The citric acid (TCA) cycle and respiratory electron transport See in Reactome	Metabolism	R-HSA-6792572 ( R-HSA-389661 ) R-HSA-6792572 Reaction Name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs See in Reactome R-HSA-71037 ( R-HSA-71064 ) R-HSA-71037 Reaction Name: alpha-ketoadipate + CoASH + NAD+ => glutaryl-CoA + CO2 + NADH + H+ See in Reactome R-HSA-71401 ( R-HSA-71403 ) R-HSA-71401 Reaction Name: alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ See in Reactome