DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0016306)

Number of enzymes:	2
Number of disease:	1
Number of reactomes:	2
Number of reactions:	4

Search results (Disease ID: MONDO:0016306)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0016306	NPC1	O15118	-	R-HSA-8964038 R-HSA-8964038 Reactome Name: LDL clearance See in Reactome	R-HSA-174824 R-HSA-174824 Reactome Name: Plasma lipoprotein assembly, remodeling, and clearance See in Reactome R-HSA-8964043 R-HSA-8964043 Reactome Name: Plasma lipoprotein clearance See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Transport of small molecules	R-HSA-8876484 ( R-HSA-8964038 ) R-HSA-8876484 Reaction Name: NPC2 transfers CHOL to NPC1 See in Reactome R-HSA-8876485 ( R-HSA-8964038 ) R-HSA-8876485 Reaction Name: CHOL translocates from lysosome membrane to ER membrane See in Reactome
MONDO:0016306	NPC2	P61916	-	R-HSA-6798695 R-HSA-6798695 Reactome Name: Neutrophil degranulation See in Reactome R-HSA-8964038 R-HSA-8964038 Reactome Name: LDL clearance See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-174824 R-HSA-174824 Reactome Name: Plasma lipoprotein assembly, remodeling, and clearance See in Reactome R-HSA-8964043 R-HSA-8964043 Reactome Name: Plasma lipoprotein clearance See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Immune System Transport of small molecules	R-HSA-6798751 ( R-HSA-6798695 ) R-HSA-6798751 Reaction Name: Exocytosis of azurophil granule lumen proteins See in Reactome R-HSA-8876472 ( R-HSA-8964038 ) R-HSA-8876472 Reaction Name: NPC2 binds CHOL See in Reactome R-HSA-8876484 ( R-HSA-8964038 ) R-HSA-8876484 Reaction Name: NPC2 transfers CHOL to NPC1 See in Reactome