DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0015802)

Number of enzymes:	4
Number of disease:	1
Number of reactomes:	17
Number of reactions:	39

Search results (Disease ID: MONDO:0015802)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0015802	RAB11A	P62491	3.6.5.2	R-HSA-8873719 R-HSA-8873719 Reactome Name: RAB geranylgeranylation See in Reactome R-HSA-8854214 R-HSA-8854214 Reactome Name: TBC/RABGAPs See in Reactome R-HSA-5620912 R-HSA-5620912 Reactome Name: Anchoring of the basal body to the plasma membrane See in Reactome R-HSA-1445148 R-HSA-1445148 Reactome Name: Translocation of SLC2A4 (GLUT4) to the plasma membrane See in Reactome R-HSA-5620916 R-HSA-5620916 Reactome Name: VxPx cargo-targeting to cilium See in Reactome R-HSA-432040 R-HSA-432040 Reactome Name: Vasopressin regulates renal water homeostasis via Aquaporins See in Reactome	R-HSA-1852241 R-HSA-1852241 Reactome Name: Organelle biogenesis and maintenance See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-199991 R-HSA-199991 Reactome Name: Membrane Trafficking See in Reactome R-HSA-445717 R-HSA-445717 Reactome Name: Aquaporin-mediated transport See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-5620920 R-HSA-5620920 Reactome Name: Cargo trafficking to the periciliary membrane See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-5617833 R-HSA-5617833 Reactome Name: Cilium Assembly See in Reactome R-HSA-9007101 R-HSA-9007101 Reactome Name: Rab regulation of trafficking See in Reactome R-HSA-5653656 R-HSA-5653656 Reactome Name: Vesicle-mediated transport See in Reactome	Organelle biogenesis and maintenance Metabolism of proteins Transport of small molecules Vesicle-mediated transport	R-HSA-2316352 ( R-HSA-1445148 ) R-HSA-2316352 Reaction Name: SLC2A4 (GLUT4) vesicle translocates and docks at the plasma membrane See in Reactome R-HSA-432237 ( R-HSA-432040 ) R-HSA-432237 Reaction Name: Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane See in Reactome R-HSA-5617816 ( R-HSA-5620912 ) R-HSA-5617816 Reaction Name: RAB3IP stimulates nucleotide exchange on RAB8A See in Reactome R-HSA-5620921 ( R-HSA-5620916 ) R-HSA-5620921 Reaction Name: ASAP1 recruits RAB11FIP3 and RAB11 to the ciliary targeting complex See in Reactome R-HSA-5623513 ( R-HSA-5620916 ) R-HSA-5623513 Reaction Name: ASAP1 stimulates GTPase activity of ARF4 See in Reactome R-HSA-5623519 ( R-HSA-5620916 ) R-HSA-5623519 Reaction Name: RAB3IP and RAB8A bind to the ciliary targeting complex See in Reactome R-HSA-5623521 ( R-HSA-5620916 ) R-HSA-5623521 Reaction Name: RAB3IP stimulates nucleotide exchange on RAB8A See in Reactome R-HSA-5623524 ( R-HSA-5620916 ) R-HSA-5623524 Reaction Name: The exocyst complex binds to RAB3IP in the ciliary targeting complex See in Reactome R-HSA-5623525 ( R-HSA-5620916 ) R-HSA-5623525 Reaction Name: Cargo-carrying vesicles bud from the TGN See in Reactome R-HSA-5623527 ( R-HSA-5620916 ) R-HSA-5623527 Reaction Name: VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane See in Reactome R-HSA-5638009 ( R-HSA-5620912 ) R-HSA-5638009 Reaction Name: CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body See in Reactome R-HSA-5638014 ( R-HSA-5620912 ) R-HSA-5638014 Reaction Name: RAB11A:GTP-containing Golgi vesicles recruit RAB3IP See in Reactome R-HSA-8854759 ( R-HSA-8854214 ) R-HSA-8854759 Reaction Name: TBC1D14 binds RAB11 and ULK1 See in Reactome R-HSA-8870466 ( R-HSA-8873719 ) R-HSA-8870466 Reaction Name: RGGT:CHM binds RABs See in Reactome R-HSA-8870469 ( R-HSA-8873719 ) R-HSA-8870469 Reaction Name: RGGT geranylgeranylates RAB proteins See in Reactome
MONDO:0015802	TAOK1	Q7L7X3	2.7.11.1	R-HSA-5663220 R-HSA-5663220 Reactome Name: RHO GTPases Activate Formins See in Reactome R-HSA-2500257 R-HSA-2500257 Reactome Name: Resolution of Sister Chromatid Cohesion See in Reactome R-HSA-2467813 R-HSA-2467813 Reactome Name: Separation of Sister Chromatids See in Reactome R-HSA-9648025 R-HSA-9648025 Reactome Name: EML4 and NUDC in mitotic spindle formation See in Reactome R-HSA-141444 R-HSA-141444 Reactome Name: Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal See in Reactome R-HSA-68877 R-HSA-68877 Reactome Name: Mitotic Prometaphase See in Reactome	R-HSA-195258 R-HSA-195258 Reactome Name: RHO GTPase Effectors See in Reactome R-HSA-2555396 R-HSA-2555396 Reactome Name: Mitotic Metaphase and Anaphase See in Reactome R-HSA-141424 R-HSA-141424 Reactome Name: Amplification of signal from the kinetochores See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-69620 R-HSA-69620 Reactome Name: Cell Cycle Checkpoints See in Reactome R-HSA-68886 R-HSA-68886 Reactome Name: M Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-68882 R-HSA-68882 Reactome Name: Mitotic Anaphase See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-69618 R-HSA-69618 Reactome Name: Mitotic Spindle Checkpoint See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Cell Cycle Signal Transduction	R-HSA-141409 ( R-HSA-141444 ) R-HSA-141409 Reaction Name: Mad1 binds kinetochore See in Reactome R-HSA-141422 ( R-HSA-141444 ) R-HSA-141422 Reaction Name: MAD2 converted to an inhibitory state via interaction with Mad1 See in Reactome R-HSA-141431 ( R-HSA-141444 ) R-HSA-141431 Reaction Name: MAD2 associates with the Mad1 kinetochore complex See in Reactome R-HSA-141439 ( R-HSA-141444 ) R-HSA-141439 Reaction Name: Release of activated MAD2 from kinetochores See in Reactome R-HSA-1638803 ( R-HSA-2500257; R-HSA-68877 ) R-HSA-1638803 Reaction Name: Phosphorylation of cohesin by PLK1 at centromeres See in Reactome R-HSA-1638821 ( R-HSA-2500257; R-HSA-68877 ) R-HSA-1638821 Reaction Name: PP2A-B56 dephosphorylates centromeric cohesin See in Reactome R-HSA-2467809 ( R-HSA-2467813 ) R-HSA-2467809 Reaction Name: ESPL1 (Separase) cleaves centromeric cohesin See in Reactome R-HSA-2467811 ( R-HSA-2467813 ) R-HSA-2467811 Reaction Name: Separation of sister chromatids See in Reactome R-HSA-2468287 ( R-HSA-2500257; R-HSA-68877 ) R-HSA-2468287 Reaction Name: CDK1 phosphorylates CDCA5 (Sororin) at centromeres See in Reactome R-HSA-2484822 ( R-HSA-2500257; R-HSA-68877 ) R-HSA-2484822 Reaction Name: Kinetochore assembly See in Reactome R-HSA-375302 ( R-HSA-68877 ) R-HSA-375302 Reaction Name: Kinetochore capture of astral microtubules See in Reactome R-HSA-5666129 ( R-HSA-5663220 ) R-HSA-5666129 Reaction Name: CDC42:GTP recruits DIAPH2-2 to kinetochores See in Reactome R-HSA-5666160 ( R-HSA-5663220 ) R-HSA-5666160 Reaction Name: AURKB phosphorylates DIAPH2-2 at kinetochores See in Reactome R-HSA-5666169 ( R-HSA-5663220 ) R-HSA-5666169 Reaction Name: Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 See in Reactome R-HSA-9648114 ( R-HSA-68877; R-HSA-9648025 ) R-HSA-9648114 Reaction Name: EML4 recruits NUDC to mitotic spindle See in Reactome
MONDO:0015802	PPP3CA	Q08209	3.1.3.16	R-HSA-2871809 R-HSA-2871809 Reactome Name: FCERI mediated Ca+2 mobilization See in Reactome R-HSA-4086398 R-HSA-4086398 Reactome Name: Ca2+ pathway See in Reactome R-HSA-180024 R-HSA-180024 Reactome Name: DARPP-32 events See in Reactome R-HSA-2025928 R-HSA-2025928 Reactome Name: Calcineurin activates NFAT See in Reactome R-HSA-5607763 R-HSA-5607763 Reactome Name: CLEC7A (Dectin-1) induces NFAT activation See in Reactome	R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-2454202 R-HSA-2454202 Reactome Name: Fc epsilon receptor (FCERI) signaling See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-3858494 R-HSA-3858494 Reactome Name: Beta-catenin independent WNT signaling See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-983705 R-HSA-983705 Reactome Name: Signaling by the B Cell Receptor (BCR) See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-1168372 R-HSA-1168372 Reactome Name: Downstream signaling events of B Cell Receptor (BCR) See in Reactome R-HSA-5607764 R-HSA-5607764 Reactome Name: CLEC7A (Dectin-1) signaling See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Immune System Signal Transduction	R-HSA-201783 ( R-HSA-180024 ) R-HSA-201783 Reaction Name: Inactive catalytic PP2B is activated by the binding of calmodulin See in Reactome R-HSA-201787 ( R-HSA-180024 ) R-HSA-201787 Reaction Name: PPP3 complex dephosphorylates DARPP-32 on Thr34 See in Reactome R-HSA-2025882 ( R-HSA-2025928 ) R-HSA-2025882 Reaction Name: Calcineurin dephosphorylates NFATC1,2,3 See in Reactome R-HSA-2025890 ( R-HSA-2025928 ) R-HSA-2025890 Reaction Name: Calcineurin binds NFATC1,2,3 See in Reactome R-HSA-2730849 ( R-HSA-2871809; R-HSA-5607763 ) R-HSA-2730849 Reaction Name: Calcineurin binds and dephosphorylates NFAT See in Reactome R-HSA-2730867 ( R-HSA-2871809; R-HSA-5607763 ) R-HSA-2730867 Reaction Name: Translocation of CaN:CaM:NFAT to nucleus See in Reactome R-HSA-2730872 ( R-HSA-2871809; R-HSA-4086398; R-HSA-5607763 ) R-HSA-2730872 Reaction Name: Activation of Calcineurin See in Reactome R-HSA-4551451 ( R-HSA-4086398 ) R-HSA-4551451 Reaction Name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling See in Reactome R-HSA-4551465 ( R-HSA-4086398 ) R-HSA-4551465 Reaction Name: Translocation of NFATC1:CaN:CaM to nucleus See in Reactome
MONDO:0015802	BRSK2	Q8IWQ3	2.7.11.26 2.7.11.1