DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0015470)

Number of enzymes:	4
Number of disease:	1
Number of reactomes:	5
Number of reactions:	9

Search results (Disease ID: MONDO:0015470)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0015470	PPCS	Q9HAB8	6.3.2.51	R-HSA-196783 R-HSA-196783 Reactome Name: Coenzyme A biosynthesis See in Reactome	R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-199220 R-HSA-199220 Reactome Name: Vitamin B5 (pantothenate) metabolism See in Reactome	Metabolism	R-HSA-196753 ( R-HSA-196783 ) R-HSA-196753 Reaction Name: 2xPPCS ligates PPanK with Cys See in Reactome
MONDO:0015470	DOLK	Q9UPQ8	2.7.1.108	R-HSA-446199 R-HSA-446199 Reactome Name: Synthesis of Dolichyl-phosphate See in Reactome	R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-446219 R-HSA-446219 Reactome Name: Synthesis of substrates in N-glycan biosythesis See in Reactome R-HSA-446193 R-HSA-446193 Reactome Name: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Metabolism of proteins	R-HSA-446195 ( R-HSA-446199 ) R-HSA-446195 Reaction Name: DOLK phosphorylates DCHOL to DOLP See in Reactome
MONDO:0015470	TXNRD2	Q9NNW7	1.8.1.9	R-HSA-3299685 R-HSA-3299685 Reactome Name: Detoxification of Reactive Oxygen Species See in Reactome	R-HSA-8953897 R-HSA-8953897 Reactome Name: Cellular responses to stimuli See in Reactome R-HSA-9711123 R-HSA-9711123 Reactome Name: Cellular response to chemical stress See in Reactome R-HSA-2262752 R-HSA-2262752 Reactome Name: Cellular responses to stress See in Reactome	Cellular responses to stimuli	R-HSA-3323050 ( R-HSA-3299685 ) R-HSA-3323050 Reaction Name: TXNRD2 catalyzes the reduction of TXN2 by NADPH See in Reactome
MONDO:0015470	TAFAZZIN	Q16635	2.3.1.-	R-HSA-1268020 R-HSA-1268020 Reactome Name: Mitochondrial protein import See in Reactome R-HSA-1482798 R-HSA-1482798 Reactome Name: Acyl chain remodeling of CL See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1483206 R-HSA-1483206 Reactome Name: Glycerophospholipid biosynthesis See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-9609507 R-HSA-9609507 Reactome Name: Protein localization See in Reactome R-HSA-1483257 R-HSA-1483257 Reactome Name: Phospholipid metabolism See in Reactome	Metabolism Protein localization	R-HSA-1299481 ( R-HSA-1268020 ) R-HSA-1299481 Reaction Name: TIMM9:TIMM10 binds hydrophobic proteins See in Reactome R-HSA-1482781 ( R-HSA-1482798 ) R-HSA-1482781 Reaction Name: MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) See in Reactome R-HSA-1482794 ( R-HSA-1482798 ) R-HSA-1482794 Reaction Name: CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) See in Reactome R-HSA-1482850 ( R-HSA-1482798 ) R-HSA-1482850 Reaction Name: MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) See in Reactome R-HSA-1482894 ( R-HSA-1482798 ) R-HSA-1482894 Reaction Name: CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) See in Reactome R-HSA-1955380 ( R-HSA-1268020 ) R-HSA-1955380 Reaction Name: TIMM9:TIMM10 transfers proteins to TIMM22 See in Reactome