DAR - Bologna Biocomputing Group

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0014919	RNF43	Q68DV7	2.3.2.27	R-HSA-4641263 R-HSA-4641263 Reactome Name: Regulation of FZD by ubiquitination See in Reactome	R-HSA-201681 R-HSA-201681 Reactome Name: TCF dependent signaling in response to WNT See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Signal Transduction	R-HSA-4641205 ( R-HSA-4641263 ) R-HSA-4641205 Reaction Name: RSPO:LGR binds ZNRF3 See in Reactome R-HSA-4641246 ( R-HSA-4641263 ) R-HSA-4641246 Reaction Name: ZNRF3 autoubiquitinates to promote its internalization See in Reactome R-HSA-4641249 ( R-HSA-4641263 ) R-HSA-4641249 Reaction Name: ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex See in Reactome R-HSA-4641253 ( R-HSA-4641263 ) R-HSA-4641253 Reaction Name: ZNRF3 ubiquitinates FZD to promote its downregulation See in Reactome