DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0013845)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	3
Number of reactions:	6

Search results (Disease ID: MONDO:0013845)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0013845	PLCB4	Q15147	3.1.4.11	R-HSA-112043 R-HSA-112043 Reactome Name: PLC beta mediated events See in Reactome R-HSA-1855204 R-HSA-1855204 Reactome Name: Synthesis of IP3 and IP4 in the cytosol See in Reactome R-HSA-416476 R-HSA-416476 Reactome Name: G alpha (q) signalling events See in Reactome	R-HSA-1483249 R-HSA-1483249 Reactome Name: Inositol phosphate metabolism See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-112040 R-HSA-112040 Reactome Name: G-protein mediated events See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Metabolism Signal Transduction	R-HSA-111870 ( R-HSA-112043 ) R-HSA-111870 Reaction Name: Activation of PLC beta-1/4 See in Reactome R-HSA-111879 ( R-HSA-112043 ) R-HSA-111879 Reaction Name: PIP2 hydrolysis See in Reactome R-HSA-112037 ( R-HSA-112043 ) R-HSA-112037 Reaction Name: Inactivation of PLC beta See in Reactome R-HSA-114688 ( R-HSA-416476 ) R-HSA-114688 Reaction Name: PLC-beta hydrolyses PIP2 to DAG and IP3 See in Reactome R-HSA-1855177 ( R-HSA-1855204 ) R-HSA-1855177 Reaction Name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane See in Reactome R-HSA-398188 ( R-HSA-416476 ) R-HSA-398188 Reaction Name: PLC beta is activated by G alpha (q) See in Reactome