DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0013539)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	5
Number of reactions:	8

Search results (Disease ID: MONDO:0013539)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0013539	LTC4S	Q16873	2.5.1.- 4.4.1.20	R-HSA-9026766 R-HSA-9026766 Reactome Name: Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR) See in Reactome R-HSA-2142691 R-HSA-2142691 Reactome Name: Synthesis of Leukotrienes (LT) and Eoxins (EX) See in Reactome R-HSA-9026762 R-HSA-9026762 Reactome Name: Biosynthesis of maresin conjugates in tissue regeneration (MCTR) See in Reactome R-HSA-2142688 R-HSA-2142688 Reactome Name: Synthesis of 5-eicosatetraenoic acids See in Reactome R-HSA-2142700 R-HSA-2142700 Reactome Name: Synthesis of Lipoxins (LX) See in Reactome	R-HSA-9018677 R-HSA-9018677 Reactome Name: Biosynthesis of DHA-derived SPMs See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-9018678 R-HSA-9018678 Reactome Name: Biosynthesis of specialized proresolving mediators (SPMs) See in Reactome R-HSA-9026395 R-HSA-9026395 Reactome Name: Biosynthesis of DHA-derived sulfido conjugates See in Reactome	Metabolism	R-HSA-2161768 ( R-HSA-2142691 ) R-HSA-2161768 Reaction Name: EXA4 is converted to EXC4 by LTC4S See in Reactome R-HSA-2161907 ( R-HSA-2142700 ) R-HSA-2161907 Reaction Name: ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 See in Reactome R-HSA-2161917 ( R-HSA-2142700 ) R-HSA-2161917 Reaction Name: ALOX5 oxidises 15S-HpETE to LXA4/B4 See in Reactome R-HSA-265296 ( R-HSA-2142688; R-HSA-2142691 ) R-HSA-265296 Reaction Name: Arachidonic acid is oxidised to 5S-HpETE by ALOX5 See in Reactome R-HSA-266050 ( R-HSA-2142691 ) R-HSA-266050 Reaction Name: LTA4 is converted to LTC4 by LTC4S See in Reactome R-HSA-266051 ( R-HSA-2142691; R-HSA-2142700 ) R-HSA-266051 Reaction Name: 5S-HpETE is dehydrated to LTA4 by ALOX5 See in Reactome R-HSA-9026780 ( R-HSA-9026762 ) R-HSA-9026780 Reaction Name: LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 See in Reactome R-HSA-9026911 ( R-HSA-9026766 ) R-HSA-9026911 Reaction Name: LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 See in Reactome