DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0013410)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	5
Number of reactions:	6

Search results (Disease ID: MONDO:0013410)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0013410	MAP3K1	Q13233	2.7.11.25	R-HSA-933542 R-HSA-933542 Reactome Name: TRAF6 mediated NF-kB activation See in Reactome R-HSA-975138 R-HSA-975138 Reactome Name: TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation See in Reactome R-HSA-2871796 R-HSA-2871796 Reactome Name: FCERI mediated MAPK activation See in Reactome R-HSA-975871 R-HSA-975871 Reactome Name: MyD88 cascade initiated on plasma membrane See in Reactome R-HSA-166058 R-HSA-166058 Reactome Name: MyD88:MAL(TIRAP) cascade initiated on plasma membrane See in Reactome	R-HSA-168188 R-HSA-168188 Reactome Name: Toll Like Receptor TLR6:TLR2 Cascade See in Reactome R-HSA-181438 R-HSA-181438 Reactome Name: Toll Like Receptor 2 (TLR2) Cascade See in Reactome R-HSA-168142 R-HSA-168142 Reactome Name: Toll Like Receptor 10 (TLR10) Cascade See in Reactome R-HSA-2454202 R-HSA-2454202 Reactome Name: Fc epsilon receptor (FCERI) signaling See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-168181 R-HSA-168181 Reactome Name: Toll Like Receptor 7/8 (TLR7/8) Cascade See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-168176 R-HSA-168176 Reactome Name: Toll Like Receptor 5 (TLR5) Cascade See in Reactome R-HSA-168898 R-HSA-168898 Reactome Name: Toll-like Receptor Cascades See in Reactome R-HSA-975155 R-HSA-975155 Reactome Name: MyD88 dependent cascade initiated on endosome See in Reactome R-HSA-168928 R-HSA-168928 Reactome Name: DDX58/IFIH1-mediated induction of interferon-alpha/beta See in Reactome R-HSA-168179 R-HSA-168179 Reactome Name: Toll Like Receptor TLR1:TLR2 Cascade See in Reactome R-HSA-166016 R-HSA-166016 Reactome Name: Toll Like Receptor 4 (TLR4) Cascade See in Reactome R-HSA-168138 R-HSA-168138 Reactome Name: Toll Like Receptor 9 (TLR9) Cascade See in Reactome	Immune System	R-HSA-166869 ( R-HSA-166058; R-HSA-975138; R-HSA-975871 ) R-HSA-166869 Reaction Name: TRAF6 binds MEKK1 See in Reactome R-HSA-2730868 ( R-HSA-2871796 ) R-HSA-2730868 Reaction Name: Phosphorylation of MEK7 by MEKK1 See in Reactome R-HSA-2730887 ( R-HSA-2871796 ) R-HSA-2730887 Reaction Name: Autophosphorylation and activation of MEKK1 See in Reactome R-HSA-2730896 ( R-HSA-2871796 ) R-HSA-2730896 Reaction Name: Phosphorylation of MEK4 by MEKK1 See in Reactome R-HSA-933528 ( R-HSA-933542 ) R-HSA-933528 Reaction Name: Interaction of MEKK1 with TRAF6 See in Reactome R-HSA-933530 ( R-HSA-933542 ) R-HSA-933530 Reaction Name: Activation of IKK by MEKK1 See in Reactome