DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0011532)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	2
Number of reactions:	6

Search results (Disease ID: MONDO:0011532)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0011532	HSPD1	P10809	5.6.1.7	R-HSA-1268020 R-HSA-1268020 Reactome Name: Mitochondrial protein import See in Reactome R-HSA-8869496 R-HSA-8869496 Reactome Name: TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation See in Reactome	R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-8864260 R-HSA-8864260 Reactome Name: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors See in Reactome R-HSA-9609507 R-HSA-9609507 Reactome Name: Protein localization See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Protein localization	R-HSA-1268022 ( R-HSA-1268020 ) R-HSA-1268022 Reaction Name: TOMM40 complex translocates proteins from the cytosol to the mitochondrial intermembrane space See in Reactome R-HSA-1299475 ( R-HSA-1268020 ) R-HSA-1299475 Reaction Name: TIMM23 PAM translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix See in Reactome R-HSA-1299478 ( R-HSA-1268020 ) R-HSA-1299478 Reaction Name: MPP cleaves targeting peptide (presequence) of matrix precursors See in Reactome R-HSA-1299480 ( R-HSA-1268020 ) R-HSA-1299480 Reaction Name: Precursor proteins enter TIMM23 PAM See in Reactome R-HSA-8869558 ( R-HSA-8869496 ) R-HSA-8869558 Reaction Name: HSPD1 gene expression is repressed by the complex of NPM1 and TFAP2A homodimer See in Reactome R-HSA-8986181 ( R-HSA-1268020 ) R-HSA-8986181 Reaction Name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) See in Reactome