DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0010187)

Number of enzymes:	2
Number of disease:	1
Number of reactomes:	2
Number of reactions:	11

Search results (Disease ID: MONDO:0010187)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0010187	VKORC1	Q9BQB6	1.17.4.4	R-HSA-6806664 R-HSA-6806664 Reactome Name: Metabolism of vitamin K See in Reactome	R-HSA-6806667 R-HSA-6806667 Reactome Name: Metabolism of fat-soluble vitamins See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-159790 ( R-HSA-6806664 ) R-HSA-159790 Reaction Name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) See in Reactome R-HSA-9026967 ( R-HSA-6806664 ) R-HSA-9026967 Reaction Name: VKORC1 inhibitors binds VKORC1 dimer See in Reactome
MONDO:0010187	GGCX	P38435	4.1.1.90	R-HSA-159740 R-HSA-159740 Reactome Name: Gamma-carboxylation of protein precursors See in Reactome	R-HSA-159854 R-HSA-159854 Reactome Name: Gamma-carboxylation, transport, and amino-terminal cleavage of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-163841 R-HSA-163841 Reactome Name: Gamma carboxylation, hypusine formation and arylsulfatase activation See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome	Metabolism of proteins	R-HSA-159752 ( R-HSA-159740 ) R-HSA-159752 Reaction Name: GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) See in Reactome R-HSA-159761 ( R-HSA-159740 ) R-HSA-159761 Reaction Name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) See in Reactome R-HSA-159795 ( R-HSA-159740 ) R-HSA-159795 Reaction Name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) See in Reactome R-HSA-159803 ( R-HSA-159740 ) R-HSA-159803 Reaction Name: GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) See in Reactome R-HSA-159819 ( R-HSA-159740 ) R-HSA-159819 Reaction Name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) See in Reactome R-HSA-159826 ( R-HSA-159740 ) R-HSA-159826 Reaction Name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) See in Reactome R-HSA-163810 ( R-HSA-159740 ) R-HSA-163810 Reaction Name: GGCX gamma-carboxylates GAS6(31-691) (pro-GAS6) See in Reactome R-HSA-163820 ( R-HSA-159740 ) R-HSA-163820 Reaction Name: GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) See in Reactome R-HSA-6807214 ( R-HSA-159740 ) R-HSA-6807214 Reaction Name: GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) See in Reactome