DAR - Bologna Biocomputing Group

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0009612	MMACHC	Q9Y4U1	2.5.1.151 1.16.1.6	R-HSA-196741 R-HSA-196741 Reactome Name: Cobalamin (Cbl, vitamin B12) transport and metabolism See in Reactome	R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-196849 R-HSA-196849 Reactome Name: Metabolism of water-soluble vitamins and cofactors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-3095889 ( R-HSA-196741 ) R-HSA-3095889 Reaction Name: MMACHC dealkylates RCbl See in Reactome R-HSA-3149494 ( R-HSA-196741 ) R-HSA-3149494 Reaction Name: MMACHC:cob(II)alamin binds MMADHC See in Reactome R-HSA-3149519 ( R-HSA-196741 ) R-HSA-3149519 Reaction Name: MMACHC decyanates CNCbl See in Reactome R-HSA-3149563 ( R-HSA-196741 ) R-HSA-3149563 Reaction Name: MMADHC targets transport of cytosolic cob(II)alamin to mitochondria See in Reactome R-HSA-3204318 ( R-HSA-196741 ) R-HSA-3204318 Reaction Name: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR See in Reactome R-HSA-9759549 ( R-HSA-196741 ) R-HSA-9759549 Reaction Name: Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin See in Reactome