DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0009124)

Number of enzymes:	2
Number of disease:	1
Number of reactomes:	2
Number of reactions:	6

Search results (Disease ID: MONDO:0009124)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0009124	NSUN2	Q08J23	2.1.1.203 2.1.1.-	R-HSA-6782315 R-HSA-6782315 Reactome Name: tRNA modification in the nucleus and cytosol See in Reactome	R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome	Metabolism of RNA	R-HSA-6782388 ( R-HSA-6782315 ) R-HSA-6782388 Reaction Name: NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA) See in Reactome R-HSA-6785409 ( R-HSA-6782315 ) R-HSA-6785409 Reaction Name: NSUN2 methylates cytidine-48 and cytidine-49 of tRNA(Asp)(GUC) See in Reactome R-HSA-6785438 ( R-HSA-6782315 ) R-HSA-6785438 Reaction Name: NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC) See in Reactome
MONDO:0009124	LIG4	P49917	6.5.1.1	R-HSA-5693571 R-HSA-5693571 Reactome Name: Nonhomologous End-Joining (NHEJ) See in Reactome	R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-5693532 R-HSA-5693532 Reactome Name: DNA Double-Strand Break Repair See in Reactome	DNA Repair	R-HSA-5687360 ( R-HSA-5693571 ) R-HSA-5687360 Reaction Name: POLL or POLM extends aligned DNA DSB ends to fill gaps See in Reactome R-HSA-5693574 ( R-HSA-5693571 ) R-HSA-5693574 Reaction Name: XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ See in Reactome R-HSA-5693604 ( R-HSA-5693571 ) R-HSA-5693604 Reaction Name: XRCC4:LIG4 ligates DNA DSB ends during NHEJ See in Reactome