DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0007763)

Number of enzymes:	3
Number of disease:	1
Number of reactomes:	8
Number of reactions:	8

Search results (Disease ID: MONDO:0007763)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007763	OGG1	O15527	4.2.99.18 3.2.2.-	R-HSA-110357 R-HSA-110357 Reactome Name: Displacement of DNA glycosylase by APEX1 See in Reactome R-HSA-110330 R-HSA-110330 Reactome Name: Recognition and association of DNA glycosylase with site containing an affected purine See in Reactome R-HSA-110331 R-HSA-110331 Reactome Name: Cleavage of the damaged purine See in Reactome R-HSA-110329 R-HSA-110329 Reactome Name: Cleavage of the damaged pyrimidine See in Reactome R-HSA-110328 R-HSA-110328 Reactome Name: Recognition and association of DNA glycosylase with site containing an affected pyrimidine See in Reactome R-HSA-5649702 R-HSA-5649702 Reactome Name: APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway See in Reactome	R-HSA-73927 R-HSA-73927 Reactome Name: Depurination See in Reactome R-HSA-73933 R-HSA-73933 Reactome Name: Resolution of Abasic Sites (AP sites) See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-73884 R-HSA-73884 Reactome Name: Base Excision Repair See in Reactome R-HSA-73928 R-HSA-73928 Reactome Name: Depyrimidination See in Reactome R-HSA-73929 R-HSA-73929 Reactome Name: Base-Excision Repair, AP Site Formation See in Reactome	DNA Repair	R-HSA-110235 ( R-HSA-110330 ) R-HSA-110235 Reaction Name: OGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine See in Reactome R-HSA-110236 ( R-HSA-110328 ) R-HSA-110236 Reaction Name: OGG1 glycosylase mediated recognition and binding of a formamidopyrimidine (FapyG) See in Reactome R-HSA-110243 ( R-HSA-110331 ) R-HSA-110243 Reaction Name: Excision of 8-oxoguanine by OGG1 glycosylase See in Reactome R-HSA-110244 ( R-HSA-110329 ) R-HSA-110244 Reaction Name: Excision of FapyG by OGG1 glycosylase See in Reactome R-HSA-110354 ( R-HSA-110357 ) R-HSA-110354 Reaction Name: Displacement of OGG1 glycosylase by APEX1 at the AP site See in Reactome R-HSA-5649701 ( R-HSA-5649702 ) R-HSA-5649701 Reaction Name: NEIL1,NEIL2 displace OGG1 from AP-dsDNA See in Reactome
MONDO:0007763	RNF139	Q8WU17	2.3.2.27	R-HSA-901032 R-HSA-901032 Reactome Name: ER Quality Control Compartment (ERQC) See in Reactome	R-HSA-532668 R-HSA-532668 Reactome Name: N-glycan trimming in the ER and Calnexin/Calreticulin cycle See in Reactome R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-901042 R-HSA-901042 Reactome Name: Calnexin/calreticulin cycle See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Metabolism of proteins	R-HSA-8867288 ( R-HSA-901032 ) R-HSA-8867288 Reaction Name: OS9:SEL1:ERAD E3 ligase:DERL2 ubiquitinates unfolded protein:(GlcNAc)2 (Man)9-5 See in Reactome
MONDO:0007763	SETD2	Q9BYW2	2.1.1.359 2.1.1.-	R-HSA-3214841 R-HSA-3214841 Reactome Name: PKMTs methylate histone lysines See in Reactome	R-HSA-4839726 R-HSA-4839726 Reactome Name: Chromatin organization See in Reactome R-HSA-3247509 R-HSA-3247509 Reactome Name: Chromatin modifying enzymes See in Reactome	Chromatin organization	R-HSA-5638141 ( R-HSA-3214841 ) R-HSA-5638141 Reaction Name: SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) See in Reactome