DAR - Bologna Biocomputing Group

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0007220	ROR2	Q01974	2.7.10.1	R-HSA-5140745 R-HSA-5140745 Reactome Name: WNT5A-dependent internalization of FZD2, FZD5 and ROR2 See in Reactome R-HSA-4086400 R-HSA-4086400 Reactome Name: PCP/CE pathway See in Reactome	R-HSA-3858494 R-HSA-3858494 Reactome Name: Beta-catenin independent WNT signaling See in Reactome R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Signal Transduction	R-HSA-4551570 ( R-HSA-4086400 ) R-HSA-4551570 Reaction Name: VANGL2 is phosphorylated in response to WNT5A See in Reactome R-HSA-4551571 ( R-HSA-4086400 ) R-HSA-4551571 Reaction Name: WNT5A binds ROR2 and VANGL2 See in Reactome R-HSA-5140741 ( R-HSA-4086400; R-HSA-5140745 ) R-HSA-5140741 Reaction Name: WNT5A binds FZD and ROR receptors See in Reactome R-HSA-5140747 ( R-HSA-4086400; R-HSA-5140745 ) R-HSA-5140747 Reaction Name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner See in Reactome