| Number of enzymes: | 1 |
| Number of disease: | 1 |
| Number of reactomes: | 2 |
| Number of reactions: | 10 |
| DiseaseID | Gene | UniProt | EC numbers | Reactomes | Expanded Reactomes | Reactome roots | Reactions |
|---|---|---|---|---|---|---|---|
| MONDO:0032606 | NDUFS8 | O00217 | 7.1.1.2 |
R-HSA-6799198 R-HSA-611105 |
R-HSA-1428517 R-HSA-1428517Reactome Name: The citric acid (TCA) cycle and respiratory electron transportSee in Reactome R-HSA-163200 R-HSA-163200Reactome Name: Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.See in Reactome |
Metabolism |
R-HSA-163217
(
R-HSA-611105
) R-HSA-6788523 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799178 ( R-HSA-611105; R-HSA-6799198 ) R-HSA-6799178Reaction Name: Intermediate 1 binds HP subcomplex to form Intermediate 2See in Reactome R-HSA-6799179Reaction Name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complexSee in Reactome R-HSA-6799191Reaction Name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplexSee in Reactome R-HSA-6799196Reaction Name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex ISee in Reactome R-HSA-6799197Reaction Name: ND4, ND5 bind the 550kDa complex to form the 815kDa complexSee in Reactome R-HSA-6799202Reaction Name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complexSee in Reactome R-HSA-6799203Reaction Name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1See in Reactome |