DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0017778)

Number of enzymes:	4
Number of disease:	1
Number of reactomes:	4
Number of reactions:	14

Search results (Disease ID: MONDO:0017778)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0017778	ALOX12B	O75342	1.13.11.-	R-HSA-2142712 R-HSA-2142712 Reactome Name: Synthesis of 12-eicosatetraenoic acid derivatives See in Reactome	R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8978868 R-HSA-8978868 Reactome Name: Fatty acid metabolism See in Reactome R-HSA-2142753 R-HSA-2142753 Reactome Name: Arachidonic acid metabolism See in Reactome	Metabolism	R-HSA-2161950 ( R-HSA-2142712 ) R-HSA-2161950 Reaction Name: Arachidonic acid is oxidised to 12R-HpETE by ALOX12B See in Reactome
MONDO:0017778	SULT2B1	O00204	2.8.2.2	R-HSA-156584 R-HSA-156584 Reactome Name: Cytosolic sulfonation of small molecules See in Reactome	R-HSA-211859 R-HSA-211859 Reactome Name: Biological oxidations See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-156580 R-HSA-156580 Reactome Name: Phase II - Conjugation of compounds See in Reactome	Metabolism	R-HSA-176494 ( R-HSA-156584 ) R-HSA-176494 Reaction Name: SULTs transfer (SO4)2- group to 27HCHOL See in Reactome R-HSA-176517 ( R-HSA-156584 ) R-HSA-176517 Reaction Name: SULTs transfer (SO4)2- group to PREG See in Reactome R-HSA-176609 ( R-HSA-156584 ) R-HSA-176609 Reaction Name: cholesterol + PAPS => cholesterol sulfate + PAP See in Reactome R-HSA-176631 ( R-HSA-156584 ) R-HSA-176631 Reaction Name: dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP See in Reactome
MONDO:0017778	SDR9C7	Q8NEX9	1.1.1.-	R-HSA-2453902 R-HSA-2453902 Reactome Name: The canonical retinoid cycle in rods (twilight vision) See in Reactome	R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome	Sensory Perception	R-HSA-2454081 ( R-HSA-2453902 ) R-HSA-2454081 Reaction Name: RDH5 oxidises 11cROL to 11cRAL See in Reactome
MONDO:0017778	TGM1	P22735	2.3.2.13	R-HSA-6809371 R-HSA-6809371 Reactome Name: Formation of the cornified envelope See in Reactome	R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-6805567 R-HSA-6805567 Reactome Name: Keratinization See in Reactome	Developmental Biology	R-HSA-6810894 ( R-HSA-6809371 ) R-HSA-6810894 Reaction Name: Envoplakin, periplakin, involucrin, SPR binding mediated by TGM1 crosslinking See in Reactome R-HSA-6810899 ( R-HSA-6809371 ) R-HSA-6810899 Reaction Name: TGM1 and involucrin bind the plasma membrane See in Reactome R-HSA-6810937 ( R-HSA-6809371 ) R-HSA-6810937 Reaction Name: Lamellar bodies bind the early cornified envelope See in Reactome R-HSA-6811539 ( R-HSA-6809371 ) R-HSA-6811539 Reaction Name: Reinforcement of the Cornified Envelope See in Reactome R-HSA-6814298 ( R-HSA-6809371 ) R-HSA-6814298 Reaction Name: Late envelope proteins bind cornified envelope:CDSN See in Reactome R-HSA-6814387 ( R-HSA-6809371 ) R-HSA-6814387 Reaction Name: CASP14 cleaves filaggrin See in Reactome R-HSA-6814734 ( R-HSA-6809371 ) R-HSA-6814734 Reaction Name: CDSN binds the cornified envelope See in Reactome R-HSA-6814764 ( R-HSA-6809371 ) R-HSA-6814764 Reaction Name: Plasma membrane resorption See in Reactome