DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0017726)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	4
Number of reactions:	5

Search results (Disease ID: MONDO:0017726)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0017726	HEXA	P06865	3.2.1.52	R-HSA-2022857 R-HSA-2022857 Reactome Name: Keratan sulfate degradation See in Reactome R-HSA-2024101 R-HSA-2024101 Reactome Name: CS/DS degradation See in Reactome R-HSA-1660662 R-HSA-1660662 Reactome Name: Glycosphingolipid metabolism See in Reactome R-HSA-2160916 R-HSA-2160916 Reactome Name: Hyaluronan uptake and degradation See in Reactome	R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-1638074 R-HSA-1638074 Reactome Name: Keratan sulfate/keratin metabolism See in Reactome R-HSA-1793185 R-HSA-1793185 Reactome Name: Chondroitin sulfate/dermatan sulfate metabolism See in Reactome R-HSA-2142845 R-HSA-2142845 Reactome Name: Hyaluronan metabolism See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1630316 R-HSA-1630316 Reactome Name: Glycosaminoglycan metabolism See in Reactome R-HSA-428157 R-HSA-428157 Reactome Name: Sphingolipid metabolism See in Reactome	Metabolism	R-HSA-1605595 ( R-HSA-1660662 ) R-HSA-1605595 Reaction Name: Hexosaminidase A cleaves GalNAc from GM2 to form GM3 See in Reactome R-HSA-1605632 ( R-HSA-1660662 ) R-HSA-1605632 Reaction Name: Both hexosaminidase A and B can cleave GalNAc from globoside See in Reactome R-HSA-1638053 ( R-HSA-2022857 ) R-HSA-1638053 Reaction Name: HEXA cleaves the terminal GalNAc from keratan sulfate See in Reactome R-HSA-2105001 ( R-HSA-2024101 ) R-HSA-2105001 Reaction Name: HEXA cleaves the terminal GalNAc from DS See in Reactome R-HSA-2162225 ( R-HSA-2160916 ) R-HSA-2162225 Reaction Name: HEXA cleaves the terminal GalNAc from small HA fragments See in Reactome