DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0017575)

Number of enzymes:	3
Number of disease:	1
Number of reactomes:	4
Number of reactions:	5

Search results (Disease ID: MONDO:0017575)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0017575	POLG	P54098	2.7.7.7
MONDO:0017575	RRM2B	Q7LG56	1.17.4.1	R-HSA-499943 R-HSA-499943 Reactome Name: Interconversion of nucleotide di- and triphosphates See in Reactome R-HSA-5628897 R-HSA-5628897 Reactome Name: TP53 Regulates Metabolic Genes See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism	R-HSA-111804 ( R-HSA-499943 ) R-HSA-111804 Reaction Name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) See in Reactome R-HSA-5632892 ( R-HSA-5628897 ) R-HSA-5632892 Reaction Name: TP53 stimulates transcription of RRM2B gene See in Reactome R-HSA-8866405 ( R-HSA-499943 ) R-HSA-8866405 Reaction Name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) See in Reactome
MONDO:0017575	TYMP	P19971	2.4.2.4	R-HSA-73614 R-HSA-73614 Reactome Name: Pyrimidine salvage See in Reactome R-HSA-73621 R-HSA-73621 Reactome Name: Pyrimidine catabolism See in Reactome	R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-8956319 R-HSA-8956319 Reactome Name: Nucleotide catabolism See in Reactome R-HSA-15869 R-HSA-15869 Reactome Name: Metabolism of nucleotides See in Reactome R-HSA-8956321 R-HSA-8956321 Reactome Name: Nucleotide salvage See in Reactome	Metabolism	R-HSA-112265 ( R-HSA-73621 ) R-HSA-112265 Reaction Name: thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] See in Reactome R-HSA-112266 ( R-HSA-73614 ) R-HSA-112266 Reaction Name: thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] See in Reactome