DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0017288)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	3
Number of reactions:	8

Search results (Disease ID: MONDO:0017288)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0017288	DICER1	Q9UPY3	3.1.26.3	R-HSA-9708296 R-HSA-9708296 Reactome Name: tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis See in Reactome R-HSA-426486 R-HSA-426486 Reactome Name: Small interfering RNA (siRNA) biogenesis See in Reactome R-HSA-203927 R-HSA-203927 Reactome Name: MicroRNA (miRNA) biogenesis See in Reactome	R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-211000 R-HSA-211000 Reactome Name: Gene Silencing by RNA See in Reactome	Gene expression (Transcription)	R-HSA-203862 ( R-HSA-203927 ) R-HSA-203862 Reaction Name: Dicer cleaves pre-miRNA to yield duplex miRNA See in Reactome R-HSA-2106614 ( R-HSA-203927 ) R-HSA-2106614 Reaction Name: Duplex miRNA is loaded into Argonaute See in Reactome R-HSA-2106615 ( R-HSA-426486 ) R-HSA-2106615 Reaction Name: Removal of siRNA passenger strand See in Reactome R-HSA-2106625 ( R-HSA-426486 ) R-HSA-2106625 Reaction Name: Duplex siRNA is loaded into Argonaute See in Reactome R-HSA-210805 ( R-HSA-203927 ) R-HSA-210805 Reaction Name: Removal of miRNA passenger strand See in Reactome R-HSA-426464 ( R-HSA-426486 ) R-HSA-426464 Reaction Name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA See in Reactome R-HSA-9708292 ( R-HSA-9708296 ) R-HSA-9708292 Reaction Name: DICER1 cleaves tRNA See in Reactome R-HSA-9708408 ( R-HSA-9708296 ) R-HSA-9708408 Reaction Name: DICER1 cleaves tRNA Lys TTT 3 in tRNA:HIV RNA hybrid See in Reactome