DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0017052)

Number of enzymes:	3
Number of disease:	1
Number of reactomes:	3
Number of reactions:	5

Search results (Disease ID: MONDO:0017052)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0017052	DBT	P11182	2.3.1.168	R-HSA-389661 R-HSA-389661 Reactome Name: Glyoxylate metabolism and glycine degradation See in Reactome R-HSA-70895 R-HSA-70895 Reactome Name: Branched-chain amino acid catabolism See in Reactome R-HSA-9013407 R-HSA-9013407 Reactome Name: RHOH GTPase cycle See in Reactome	R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Metabolism Signal Transduction	R-HSA-5693148 ( R-HSA-70895 ) R-HSA-5693148 Reaction Name: BCKDK phosphorylates BCKDH See in Reactome R-HSA-5693153 ( R-HSA-70895 ) R-HSA-5693153 Reaction Name: PPM1K dephosphorylates p-BCKDH See in Reactome R-HSA-6792572 ( R-HSA-389661 ) R-HSA-6792572 Reaction Name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs See in Reactome R-HSA-70713 ( R-HSA-70895 ) R-HSA-70713 Reaction Name: BCKDH transfers CoA group from CoA-SH to BCAAs See in Reactome R-HSA-9018758 ( R-HSA-9013407 ) R-HSA-9018758 Reaction Name: RHOH binds effectors at the plasma membrane See in Reactome
MONDO:0017052	BCKDHB	P21953	1.2.4.4	R-HSA-389661 R-HSA-389661 Reactome Name: Glyoxylate metabolism and glycine degradation See in Reactome R-HSA-70895 R-HSA-70895 Reactome Name: Branched-chain amino acid catabolism See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-5693148 ( R-HSA-70895 ) R-HSA-5693148 Reaction Name: BCKDK phosphorylates BCKDH See in Reactome R-HSA-5693153 ( R-HSA-70895 ) R-HSA-5693153 Reaction Name: PPM1K dephosphorylates p-BCKDH See in Reactome R-HSA-6792572 ( R-HSA-389661 ) R-HSA-6792572 Reaction Name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs See in Reactome R-HSA-70713 ( R-HSA-70895 ) R-HSA-70713 Reaction Name: BCKDH transfers CoA group from CoA-SH to BCAAs See in Reactome
MONDO:0017052	BCKDHA	P12694	1.2.4.4	R-HSA-389661 R-HSA-389661 Reactome Name: Glyoxylate metabolism and glycine degradation See in Reactome R-HSA-70895 R-HSA-70895 Reactome Name: Branched-chain amino acid catabolism See in Reactome	R-HSA-71291 R-HSA-71291 Reactome Name: Metabolism of amino acids and derivatives See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome	Metabolism	R-HSA-5693148 ( R-HSA-70895 ) R-HSA-5693148 Reaction Name: BCKDK phosphorylates BCKDH See in Reactome R-HSA-5693153 ( R-HSA-70895 ) R-HSA-5693153 Reaction Name: PPM1K dephosphorylates p-BCKDH See in Reactome R-HSA-6792572 ( R-HSA-389661 ) R-HSA-6792572 Reaction Name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DHs See in Reactome R-HSA-70713 ( R-HSA-70895 ) R-HSA-70713 Reaction Name: BCKDH transfers CoA group from CoA-SH to BCAAs See in Reactome