DAR - Bologna Biocomputing Group

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DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0015085	TGM1	P22735	2.3.2.13	R-HSA-6809371 R-HSA-6809371 Reactome Name: Formation of the cornified envelope See in Reactome	R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-6805567 R-HSA-6805567 Reactome Name: Keratinization See in Reactome	Developmental Biology	R-HSA-6810894 ( R-HSA-6809371 ) R-HSA-6810894 Reaction Name: Envoplakin, periplakin, involucrin, SPR binding mediated by TGM1 crosslinking See in Reactome R-HSA-6810899 ( R-HSA-6809371 ) R-HSA-6810899 Reaction Name: TGM1 and involucrin bind the plasma membrane See in Reactome R-HSA-6810937 ( R-HSA-6809371 ) R-HSA-6810937 Reaction Name: Lamellar bodies bind the early cornified envelope See in Reactome R-HSA-6811539 ( R-HSA-6809371 ) R-HSA-6811539 Reaction Name: Reinforcement of the Cornified Envelope See in Reactome R-HSA-6814298 ( R-HSA-6809371 ) R-HSA-6814298 Reaction Name: Late envelope proteins bind cornified envelope:CDSN See in Reactome R-HSA-6814387 ( R-HSA-6809371 ) R-HSA-6814387 Reaction Name: CASP14 cleaves filaggrin See in Reactome R-HSA-6814734 ( R-HSA-6809371 ) R-HSA-6814734 Reaction Name: CDSN binds the cornified envelope See in Reactome R-HSA-6814764 ( R-HSA-6809371 ) R-HSA-6814764 Reaction Name: Plasma membrane resorption See in Reactome

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