DAR - Bologna Biocomputing Group

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0014809	DDX41	Q9UJV9	3.6.4.13	R-HSA-3270619 R-HSA-3270619 Reactome Name: IRF3-mediated induction of type I IFN See in Reactome R-HSA-1834941 R-HSA-1834941 Reactome Name: STING mediated induction of host immune responses See in Reactome R-HSA-3134975 R-HSA-3134975 Reactome Name: Regulation of innate immune responses to cytosolic DNA See in Reactome	R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-1834949 R-HSA-1834949 Reactome Name: Cytosolic sensors of pathogen-associated DNA See in Reactome	Immune System	R-HSA-1834939 ( R-HSA-1834941; R-HSA-3270619 ) R-HSA-1834939 Reaction Name: STING recruits TBK1 and IRF3 See in Reactome R-HSA-3134822 ( R-HSA-1834941 ) R-HSA-3134822 Reaction Name: DDX41 binds viral dsDNA See in Reactome R-HSA-3134946 ( R-HSA-3134975 ) R-HSA-3134946 Reaction Name: DDX41 ubiquitination by TRIM21 See in Reactome R-HSA-9013869 ( R-HSA-1834941 ) R-HSA-9013869 Reaction Name: DDX41 binds bacterial c-di-AMP, c-di-GMP See in Reactome