| Number of enzymes: | 1 |
| Number of disease: | 1 |
| Number of reactomes: | 3 |
| Number of reactions: | 9 |
| DiseaseID | Gene | UniProt | EC numbers | Reactomes | Expanded Reactomes | Reactome roots | Reactions |
|---|---|---|---|---|---|---|---|
| MONDO:0014630 | NTHL1 | P78549 |
4.2.99.18 3.2.2.- |
R-HSA-110329 R-HSA-110328 R-HSA-110328Reactome Name: Recognition and association of DNA glycosylase with site containing an affected pyrimidineSee in Reactome |
R-HSA-73894 R-HSA-73928 R-HSA-73884 R-HSA-73933 R-HSA-73929 |
DNA Repair |
R-HSA-110208
(
R-HSA-110328
) R-HSA-110208Reaction Name: NTHL1 glycosylase mediated recognition and binding of cytosine glycolSee in Reactome R-HSA-110211Reaction Name: NTHL1 glycosylase mediated recognition and binding of thymine glycolSee in Reactome R-HSA-110212Reaction Name: NTHL1 glycosylase mediated recognition and binding of dihydrouracilSee in Reactome R-HSA-110213Reaction Name: NTHL1 glycosylase mediated recognition and binding of formamidopyrimidine (FapyA)See in Reactome R-HSA-110226 ( R-HSA-110329 ) R-HSA-110227 ( R-HSA-110329 ) R-HSA-110229 ( R-HSA-110329 ) R-HSA-110229Reaction Name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylaseSee in Reactome R-HSA-110352Reaction Name: Displacement of NTHL1 glycosylase by APEX1 at the AP siteSee in Reactome |