DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0014518)

Number of enzymes:	2
Number of disease:	1
Number of reactomes:	24
Number of reactions:	30

Search results (Disease ID: MONDO:0014518)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0014518	PRKACG	P22612	2.7.11.11	R-HSA-442720 R-HSA-442720 Reactome Name: CREB1 phosphorylation through the activation of Adenylate Cyclase See in Reactome R-HSA-381676 R-HSA-381676 Reactome Name: Glucagon-like Peptide-1 (GLP1) regulates insulin secretion See in Reactome R-HSA-983231 R-HSA-983231 Reactome Name: Factors involved in megakaryocyte development and platelet production See in Reactome R-HSA-432040 R-HSA-432040 Reactome Name: Vasopressin regulates renal water homeostasis via Aquaporins See in Reactome R-HSA-5610783 R-HSA-5610783 Reactome Name: Degradation of GLI2 by the proteasome See in Reactome R-HSA-111931 R-HSA-111931 Reactome Name: PKA-mediated phosphorylation of CREB See in Reactome R-HSA-180024 R-HSA-180024 Reactome Name: DARPP-32 events See in Reactome R-HSA-5610787 R-HSA-5610787 Reactome Name: Hedgehog 'off' state See in Reactome R-HSA-163615 R-HSA-163615 Reactome Name: PKA activation See in Reactome R-HSA-5610785 R-HSA-5610785 Reactome Name: GLI3 is processed to GLI3R by the proteasome See in Reactome R-HSA-164378 R-HSA-164378 Reactome Name: PKA activation in glucagon signalling See in Reactome R-HSA-8853659 R-HSA-8853659 Reactome Name: RET signaling See in Reactome R-HSA-9010642 R-HSA-9010642 Reactome Name: ROBO receptors bind AKAP5 See in Reactome R-HSA-4420097 R-HSA-4420097 Reactome Name: VEGFA-VEGFR2 Pathway See in Reactome R-HSA-9634600 R-HSA-9634600 Reactome Name: Regulation of glycolysis by fructose 2,6-bisphosphate metabolism See in Reactome R-HSA-5687128 R-HSA-5687128 Reactome Name: MAPK6/MAPK4 signaling See in Reactome R-HSA-163560 R-HSA-163560 Reactome Name: Triglyceride catabolism See in Reactome R-HSA-5610780 R-HSA-5610780 Reactome Name: Degradation of GLI1 by the proteasome See in Reactome R-HSA-8963896 R-HSA-8963896 Reactome Name: HDL assembly See in Reactome R-HSA-392517 R-HSA-392517 Reactome Name: Rap1 signalling See in Reactome R-HSA-163358 R-HSA-163358 Reactome Name: PKA-mediated phosphorylation of key metabolic factors See in Reactome R-HSA-422356 R-HSA-422356 Reactome Name: Regulation of insulin secretion See in Reactome R-HSA-5621575 R-HSA-5621575 Reactome Name: CD209 (DC-SIGN) signaling See in Reactome	R-HSA-376176 R-HSA-376176 Reactome Name: Signaling by ROBO receptors See in Reactome R-HSA-70326 R-HSA-70326 Reactome Name: Glucose metabolism See in Reactome R-HSA-111997 R-HSA-111997 Reactome Name: CaM pathway See in Reactome R-HSA-111996 R-HSA-111996 Reactome Name: Ca-dependent events See in Reactome R-HSA-418594 R-HSA-418594 Reactome Name: G alpha (i) signalling events See in Reactome R-HSA-5358351 R-HSA-5358351 Reactome Name: Signaling by Hedgehog See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-9006925 R-HSA-9006925 Reactome Name: Intracellular signaling by second messengers See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-438064 R-HSA-438064 Reactome Name: Post NMDA receptor activation events See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-1489509 R-HSA-1489509 Reactome Name: DAG and IP3 signaling See in Reactome R-HSA-111933 R-HSA-111933 Reactome Name: Calmodulin induced events See in Reactome R-HSA-5683057 R-HSA-5683057 Reactome Name: MAPK family signaling cascades See in Reactome R-HSA-194138 R-HSA-194138 Reactome Name: Signaling by VEGF See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-8979227 R-HSA-8979227 Reactome Name: Triglyceride metabolism See in Reactome R-HSA-112316 R-HSA-112316 Reactome Name: Neuronal System See in Reactome R-HSA-372790 R-HSA-372790 Reactome Name: Signaling by GPCR See in Reactome R-HSA-112314 R-HSA-112314 Reactome Name: Neurotransmitter receptors and postsynaptic signal transmission See in Reactome R-HSA-112315 R-HSA-112315 Reactome Name: Transmission across Chemical Synapses See in Reactome R-HSA-5621481 R-HSA-5621481 Reactome Name: C-type lectin receptors (CLRs) See in Reactome R-HSA-174824 R-HSA-174824 Reactome Name: Plasma lipoprotein assembly, remodeling, and clearance See in Reactome R-HSA-388396 R-HSA-388396 Reactome Name: GPCR downstream signalling See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-163685 R-HSA-163685 Reactome Name: Integration of energy metabolism See in Reactome R-HSA-445717 R-HSA-445717 Reactome Name: Aquaporin-mediated transport See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-70171 R-HSA-70171 Reactome Name: Glycolysis See in Reactome R-HSA-8963898 R-HSA-8963898 Reactome Name: Plasma lipoprotein assembly See in Reactome R-HSA-442755 R-HSA-442755 Reactome Name: Activation of NMDA receptors and postsynaptic events See in Reactome R-HSA-163359 R-HSA-163359 Reactome Name: Glucagon signaling in metabolic regulation See in Reactome R-HSA-112043 R-HSA-112043 Reactome Name: PLC beta mediated events See in Reactome R-HSA-112040 R-HSA-112040 Reactome Name: G-protein mediated events See in Reactome R-HSA-71387 R-HSA-71387 Reactome Name: Metabolism of carbohydrates See in Reactome R-HSA-111885 R-HSA-111885 Reactome Name: Opioid Signalling See in Reactome R-HSA-9006934 R-HSA-9006934 Reactome Name: Signaling by Receptor Tyrosine Kinases See in Reactome R-HSA-422475 R-HSA-422475 Reactome Name: Axon guidance See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Immune System Transport of small molecules Metabolism Developmental Biology Neuronal System Hemostasis Signal Transduction	R-HSA-111919 ( R-HSA-111931; R-HSA-442720 ) R-HSA-111919 Reaction Name: PKA phosphorylates CREB1 See in Reactome R-HSA-111924 ( R-HSA-111931; R-HSA-442720 ) R-HSA-111924 Reaction Name: PKA catalytic subunit translocates to the nucleus See in Reactome R-HSA-111925 ( R-HSA-111931; R-HSA-163615; R-HSA-164378; R-HSA-180024; R-HSA-432040; R-HSA-442720 ) R-HSA-111925 Reaction Name: cAMP induces dissociation of inactive PKA tetramers See in Reactome R-HSA-163416 ( R-HSA-163560 ) R-HSA-163416 Reaction Name: hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP See in Reactome R-HSA-163418 ( R-HSA-163560 ) R-HSA-163418 Reaction Name: perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP See in Reactome R-HSA-163672 ( R-HSA-163358 ) R-HSA-163672 Reaction Name: Phosphorylation of ChREBP at Thr(666) by PKA See in Reactome R-HSA-163676 ( R-HSA-163358 ) R-HSA-163676 Reaction Name: Phosphorylation of pChREBP (Thr 666) at Ser(196) by PKA See in Reactome R-HSA-163773 ( R-HSA-163358; R-HSA-9634600 ) R-HSA-163773 Reaction Name: Phosphorylation of PF2K-Pase by PKA catalytic subunit See in Reactome R-HSA-177275 ( R-HSA-180024 ) R-HSA-177275 Reaction Name: PKA phosphorylates DARPP-32 on Thr34 See in Reactome R-HSA-177284 ( R-HSA-180024 ) R-HSA-177284 Reaction Name: PKA phosphorylates PDE4B See in Reactome R-HSA-265682 ( R-HSA-422356 ) R-HSA-265682 Reaction Name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel See in Reactome R-HSA-381644 ( R-HSA-381676; R-HSA-422356 ) R-HSA-381644 Reaction Name: ER calcium channels open in response to activated PKA See in Reactome R-HSA-381707 ( R-HSA-381676; R-HSA-422356 ) R-HSA-381707 Reaction Name: PKA:AKAP79:IQGAP1 complex dissociates to active PKA subunits in response to cAMP See in Reactome R-HSA-381713 ( R-HSA-381676; R-HSA-422356 ) R-HSA-381713 Reaction Name: Potassium voltage-gated channels close in reponse to PKA See in Reactome R-HSA-432232 ( R-HSA-432040 ) R-HSA-432232 Reaction Name: Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) See in Reactome R-HSA-5218854 ( R-HSA-4420097 ) R-HSA-5218854 Reaction Name: p-Y420-FYN is phosphorylated on S21 See in Reactome R-HSA-5610717 ( R-HSA-5610783; R-HSA-5610787 ) R-HSA-5610717 Reaction Name: PKA phosphorylates GLI2 See in Reactome R-HSA-5610720 ( R-HSA-5610785; R-HSA-5610787 ) R-HSA-5610720 Reaction Name: PKA phosphorylates GLI3 See in Reactome R-HSA-5610741 ( R-HSA-5610780; R-HSA-5610787 ) R-HSA-5610741 Reaction Name: PKA phosphorylates GLI1 See in Reactome R-HSA-5610749 ( R-HSA-5610787 ) R-HSA-5610749 Reaction Name: cAMP dissociates PKA, promoting GLI processing See in Reactome R-HSA-5624473 ( R-HSA-5621575 ) R-HSA-5624473 Reaction Name: Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit See in Reactome R-HSA-5682101 ( R-HSA-8963896 ) R-HSA-5682101 Reaction Name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer See in Reactome R-HSA-5687088 ( R-HSA-5687128 ) R-HSA-5687088 Reaction Name: PKA phosphorylates MAPKAPK5 See in Reactome R-HSA-8854908 ( R-HSA-8853659 ) R-HSA-8854908 Reaction Name: PKA phosphorylates RET:GDNF:GFRA dimer See in Reactome R-HSA-8951727 ( R-HSA-111931; R-HSA-163615; R-HSA-180024; R-HSA-432040; R-HSA-442720 ) R-HSA-8951727 Reaction Name: cAMP binds PKA tetramer See in Reactome R-HSA-9010641 ( R-HSA-9010642 ) R-HSA-9010641 Reaction Name: AKAP5 recruits PKA to ROBO2 See in Reactome R-HSA-913996 ( R-HSA-392517 ) R-HSA-913996 Reaction Name: PKA/PKG phosphorylate Rap1GAP2 See in Reactome R-HSA-992708 ( R-HSA-983231 ) R-HSA-992708 Reaction Name: Dual-specific AKAPs bind type I and II PKA regulatory subunits See in Reactome
MONDO:0014518	GNE	Q9Y223	3.2.1.183 2.7.1.60	R-HSA-4085001 R-HSA-4085001 Reactome Name: Sialic acid metabolism See in Reactome	R-HSA-446203 R-HSA-446203 Reactome Name: Asparagine N-linked glycosylation See in Reactome R-HSA-446219 R-HSA-446219 Reactome Name: Synthesis of substrates in N-glycan biosythesis See in Reactome R-HSA-446193 R-HSA-446193 Reactome Name: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome	Metabolism of proteins	R-HSA-4085021 ( R-HSA-4085001 ) R-HSA-4085021 Reaction Name: GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP See in Reactome R-HSA-4085028 ( R-HSA-4085001 ) R-HSA-4085028 Reaction Name: GNE phosphorylates ManNAc to ManNAc-6-P See in Reactome