DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0013872)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	4
Number of reactions:	4

Search results (Disease ID: MONDO:0013872)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0013872	ELAC2	Q9BQ52	3.1.26.11	R-HSA-9708296 R-HSA-9708296 Reactome Name: tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis See in Reactome R-HSA-6785470 R-HSA-6785470 Reactome Name: tRNA processing in the mitochondrion See in Reactome R-HSA-6784531 R-HSA-6784531 Reactome Name: tRNA processing in the nucleus See in Reactome R-HSA-8868766 R-HSA-8868766 Reactome Name: rRNA processing in the mitochondrion See in Reactome	R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-211000 R-HSA-211000 Reactome Name: Gene Silencing by RNA See in Reactome R-HSA-8953854 R-HSA-8953854 Reactome Name: Metabolism of RNA See in Reactome R-HSA-72312 R-HSA-72312 Reactome Name: rRNA processing See in Reactome R-HSA-72306 R-HSA-72306 Reactome Name: tRNA processing See in Reactome	Gene expression (Transcription) Metabolism of RNA	R-HSA-5696815 ( R-HSA-6784531 ) R-HSA-5696815 Reaction Name: ELAC2 cleaves the 3' end of pre-tRNA See in Reactome R-HSA-6785722 ( R-HSA-6785470; R-HSA-8868766 ) R-HSA-6785722 Reaction Name: Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript See in Reactome R-HSA-6786854 ( R-HSA-6785470 ) R-HSA-6786854 Reaction Name: Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript See in Reactome R-HSA-9708812 ( R-HSA-9708296 ) R-HSA-9708812 Reaction Name: ELAC2 cleaves pre-tRNA to yield 3' trailer (type II tRF or tRF-1) See in Reactome