DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0013437)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	3
Number of reactions:	5

Search results (Disease ID: MONDO:0013437)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0013437	PDE6A	P16499	3.1.4.35	R-HSA-4086398 R-HSA-4086398 Reactome Name: Ca2+ pathway See in Reactome R-HSA-2514859 R-HSA-2514859 Reactome Name: Inactivation, recovery and regulation of the phototransduction cascade See in Reactome R-HSA-2485179 R-HSA-2485179 Reactome Name: Activation of the phototransduction cascade See in Reactome	R-HSA-195721 R-HSA-195721 Reactome Name: Signaling by WNT See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome R-HSA-3858494 R-HSA-3858494 Reactome Name: Beta-catenin independent WNT signaling See in Reactome R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-2514856 R-HSA-2514856 Reactome Name: The phototransduction cascade See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Sensory Perception Signal Transduction	R-HSA-2584246 ( R-HSA-2514859 ) R-HSA-2584246 Reaction Name: GNAT1-GTP hydrolyses its bound GTP to GDP See in Reactome R-HSA-4086392 ( R-HSA-4086398 ) R-HSA-4086392 Reaction Name: PDE6 hydrolyses cGMP to GMP See in Reactome R-HSA-4086393 ( R-HSA-4086398 ) R-HSA-4086393 Reaction Name: G alpha t2 binds and activates PDE6 See in Reactome R-HSA-74059 ( R-HSA-2485179 ) R-HSA-74059 Reaction Name: PDE6 hydrolyses cGMP to GMP See in Reactome R-HSA-74065 ( R-HSA-2485179 ) R-HSA-74065 Reaction Name: GNAT1-GTP binds PDE6 and activates it See in Reactome