DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0011996)

Number of enzymes:	2
Number of disease:	1
Number of reactomes:	17
Number of reactions:	29

Search results (Disease ID: MONDO:0011996)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0011996	ABL1	P00519	2.7.10.2	R-HSA-5663213 R-HSA-5663213 Reactome Name: RHO GTPases Activate WASPs and WAVEs See in Reactome R-HSA-2029482 R-HSA-2029482 Reactome Name: Regulation of actin dynamics for phagocytic cup formation See in Reactome R-HSA-8940973 R-HSA-8940973 Reactome Name: RUNX2 regulates osteoblast differentiation See in Reactome R-HSA-5693565 R-HSA-5693565 Reactome Name: Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks See in Reactome R-HSA-5685938 R-HSA-5685938 Reactome Name: HDR through Single Strand Annealing (SSA) See in Reactome R-HSA-8939236 R-HSA-8939236 Reactome Name: RUNX1 regulates transcription of genes involved in differentiation of HSCs See in Reactome R-HSA-69231 R-HSA-69231 Reactome Name: Cyclin D associated events in G1 See in Reactome R-HSA-428890 R-HSA-428890 Reactome Name: Role of ABL in ROBO-SLIT signaling See in Reactome R-HSA-983231 R-HSA-983231 Reactome Name: Factors involved in megakaryocyte development and platelet production See in Reactome R-HSA-525793 R-HSA-525793 Reactome Name: Myogenesis See in Reactome	R-HSA-376176 R-HSA-376176 Reactome Name: Signaling by ROBO receptors See in Reactome R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-9675108 R-HSA-9675108 Reactome Name: Nervous system development See in Reactome R-HSA-1640170 R-HSA-1640170 Reactome Name: Cell Cycle See in Reactome R-HSA-1266738 R-HSA-1266738 Reactome Name: Developmental Biology See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-5693606 R-HSA-5693606 Reactome Name: DNA Double Strand Break Response See in Reactome R-HSA-8878171 R-HSA-8878171 Reactome Name: Transcriptional regulation by RUNX1 See in Reactome R-HSA-69236 R-HSA-69236 Reactome Name: G1 Phase See in Reactome R-HSA-69278 R-HSA-69278 Reactome Name: Cell Cycle, Mitotic See in Reactome R-HSA-453279 R-HSA-453279 Reactome Name: Mitotic G1 phase and G1/S transition See in Reactome R-HSA-2029480 R-HSA-2029480 Reactome Name: Fcgamma receptor (FCGR) dependent phagocytosis See in Reactome R-HSA-5693567 R-HSA-5693567 Reactome Name: HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) See in Reactome R-HSA-168249 R-HSA-168249 Reactome Name: Innate Immune System See in Reactome R-HSA-422475 R-HSA-422475 Reactome Name: Axon guidance See in Reactome R-HSA-195258 R-HSA-195258 Reactome Name: RHO GTPase Effectors See in Reactome R-HSA-5693538 R-HSA-5693538 Reactome Name: Homology Directed Repair See in Reactome R-HSA-8878166 R-HSA-8878166 Reactome Name: Transcriptional regulation by RUNX2 See in Reactome R-HSA-73894 R-HSA-73894 Reactome Name: DNA Repair See in Reactome R-HSA-5693532 R-HSA-5693532 Reactome Name: DNA Double-Strand Break Repair See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-8941326 R-HSA-8941326 Reactome Name: RUNX2 regulates bone development See in Reactome R-HSA-109582 R-HSA-109582 Reactome Name: Hemostasis See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome	Immune System Cell Cycle Developmental Biology Gene expression (Transcription) DNA Repair Hemostasis Signal Transduction	R-HSA-1013833 ( R-HSA-983231 ) R-HSA-1013833 Reaction Name: Cables link CDK5 and ABL1 See in Reactome R-HSA-2130194 ( R-HSA-2029482; R-HSA-5663213 ) R-HSA-2130194 Reaction Name: ABL phosphorylates WAVEs See in Reactome R-HSA-376141 ( R-HSA-428890 ) R-HSA-376141 Reaction Name: Interaction of ABL with ROBO1:SLIT2 See in Reactome R-HSA-428883 ( R-HSA-428890 ) R-HSA-428883 Reaction Name: Recruitment of CAP to ABL See in Reactome R-HSA-428885 ( R-HSA-428890 ) R-HSA-428885 Reaction Name: Activation of CLASP See in Reactome R-HSA-428888 ( R-HSA-428890 ) R-HSA-428888 Reaction Name: Phosphorylation of ROBO1 by ABL kinase See in Reactome R-HSA-448951 ( R-HSA-525793 ) R-HSA-448951 Reaction Name: Activation of p38 alpha/beta MAPK See in Reactome R-HSA-448957 ( R-HSA-525793 ) R-HSA-448957 Reaction Name: Interaction of p38 MAPK with JLP See in Reactome R-HSA-448958 ( R-HSA-525793 ) R-HSA-448958 Reaction Name: Nuclear translocation of p38 MAPK See in Reactome R-HSA-449200 ( R-HSA-525793 ) R-HSA-449200 Reaction Name: Interaction of ABL1 with CDO complex See in Reactome R-HSA-5686578 ( R-HSA-5693565 ) R-HSA-5686578 Reaction Name: Activated ATM phosphorylates ABL1 See in Reactome R-HSA-5686587 ( R-HSA-5685938 ) R-HSA-5686587 Reaction Name: ABL1 phosphorylates RAD52 See in Reactome R-HSA-8942607 ( R-HSA-69231 ) R-HSA-8942607 Reaction Name: Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes See in Reactome R-HSA-8956639 ( R-HSA-8939236 ) R-HSA-8956639 Reaction Name: RUNX1 binds YAP1 See in Reactome R-HSA-8956659 ( R-HSA-8939236 ) R-HSA-8956659 Reaction Name: ABL1 phosphorylates YAP1 See in Reactome R-HSA-8985227 ( R-HSA-8940973 ) R-HSA-8985227 Reaction Name: The complex of RUNX2 and WWTR1 (TAZ) binds the BGLAP gene promoter See in Reactome
MONDO:0011996	BCR	P11274	2.7.11.1	R-HSA-9013106 R-HSA-9013106 Reactome Name: RHOC GTPase cycle See in Reactome R-HSA-8980692 R-HSA-8980692 Reactome Name: RHOA GTPase cycle See in Reactome R-HSA-9013026 R-HSA-9013026 Reactome Name: RHOB GTPase cycle See in Reactome R-HSA-9013423 R-HSA-9013423 Reactome Name: RAC3 GTPase cycle See in Reactome R-HSA-9013404 R-HSA-9013404 Reactome Name: RAC2 GTPase cycle See in Reactome R-HSA-9013149 R-HSA-9013149 Reactome Name: RAC1 GTPase cycle See in Reactome R-HSA-9013148 R-HSA-9013148 Reactome Name: CDC42 GTPase cycle See in Reactome	R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-9716542 R-HSA-9716542 Reactome Name: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 See in Reactome R-HSA-194315 R-HSA-194315 Reactome Name: Signaling by Rho GTPases See in Reactome R-HSA-9012999 R-HSA-9012999 Reactome Name: RHO GTPase cycle See in Reactome	Signal Transduction	R-HSA-8980691 ( R-HSA-8980692 ) R-HSA-8980691 Reaction Name: RHOA GEFs activate RHOA See in Reactome R-HSA-8981637 ( R-HSA-8980692 ) R-HSA-8981637 Reaction Name: RHOA GAPs stimulate RHOA GTPase activity See in Reactome R-HSA-9013022 ( R-HSA-9013026 ) R-HSA-9013022 Reaction Name: RHOB GAPs stimulate RHOB GTPase activity See in Reactome R-HSA-9013024 ( R-HSA-9013026 ) R-HSA-9013024 Reaction Name: RHOB binds effectors at the plasma membrane See in Reactome R-HSA-9013110 ( R-HSA-9013106 ) R-HSA-9013110 Reaction Name: RHOC binds effectors at the plasma membrane See in Reactome R-HSA-9013111 ( R-HSA-9013106 ) R-HSA-9013111 Reaction Name: RHOC GAPs stimulate RHOC GTPase activity See in Reactome R-HSA-9013143 ( R-HSA-9013149 ) R-HSA-9013143 Reaction Name: RAC1 GEFs activate RAC1 See in Reactome R-HSA-9013144 ( R-HSA-9013149 ) R-HSA-9013144 Reaction Name: RAC1 GAPs stimulate RAC1 GTPase activity See in Reactome R-HSA-9013159 ( R-HSA-9013148 ) R-HSA-9013159 Reaction Name: CDC42 GEFs activate CDC42 See in Reactome R-HSA-9013161 ( R-HSA-9013148 ) R-HSA-9013161 Reaction Name: CDC42 GAPs stimulate CDC42 GTPase activity See in Reactome R-HSA-9014295 ( R-HSA-9013404 ) R-HSA-9014295 Reaction Name: RAC2 GAPs stimulate RAC2 GTPase activity See in Reactome R-HSA-9014296 ( R-HSA-9013404 ) R-HSA-9014296 Reaction Name: RAC2 GEFs activate RAC2 See in Reactome R-HSA-9018806 ( R-HSA-9013423 ) R-HSA-9018806 Reaction Name: RAC3 GAPs stimulate RAC3 GTPase activity See in Reactome