DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0011393)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	3
Number of reactions:	9

Search results (Disease ID: MONDO:0011393)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0011393	ABCA1	O95477	7.6.2.1	R-HSA-1989781 R-HSA-1989781 Reactome Name: PPARA activates gene expression See in Reactome R-HSA-9029569 R-HSA-9029569 Reactome Name: NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux See in Reactome R-HSA-8963896 R-HSA-8963896 Reactome Name: HDL assembly See in Reactome	R-HSA-174824 R-HSA-174824 Reactome Name: Plasma lipoprotein assembly, remodeling, and clearance See in Reactome R-HSA-400206 R-HSA-400206 Reactome Name: Regulation of lipid metabolism by PPARalpha See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome R-HSA-9006931 R-HSA-9006931 Reactome Name: Signaling by Nuclear Receptors See in Reactome R-HSA-8963898 R-HSA-8963898 Reactome Name: Plasma lipoprotein assembly See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-556833 R-HSA-556833 Reactome Name: Metabolism of lipids See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-9024446 R-HSA-9024446 Reactome Name: NR1H2 and NR1H3-mediated signaling See in Reactome	Transport of small molecules Signal Transduction Metabolism	R-HSA-1989765 ( R-HSA-1989781 ) R-HSA-1989765 Reaction Name: Expression of ABCA1 See in Reactome R-HSA-216723 ( R-HSA-8963896 ) R-HSA-216723 Reaction Name: 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane See in Reactome R-HSA-216727 ( R-HSA-8963896 ) R-HSA-216727 Reaction Name: 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 See in Reactome R-HSA-216757 ( R-HSA-8963896 ) R-HSA-216757 Reaction Name: 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane See in Reactome R-HSA-5682084 ( R-HSA-8963896 ) R-HSA-5682084 Reaction Name: ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer See in Reactome R-HSA-5682101 ( R-HSA-8963896 ) R-HSA-5682101 Reaction Name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer See in Reactome R-HSA-5682103 ( R-HSA-8963896 ) R-HSA-5682103 Reaction Name: 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane See in Reactome R-HSA-9618479 ( R-HSA-9029569 ) R-HSA-9618479 Reaction Name: ABCA1 mRNA is translated See in Reactome R-HSA-9619756 ( R-HSA-9029569 ) R-HSA-9619756 Reaction Name: NR1H2 binds ABCA1 See in Reactome