DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0010461)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	3
Number of reactions:	7

Search results (Disease ID: MONDO:0010461)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0010461	UBE2A	P49459	2.3.2.23	R-HSA-8866652 R-HSA-8866652 Reactome Name: Synthesis of active ubiquitin: roles of E1 and E2 enzymes See in Reactome R-HSA-983168 R-HSA-983168 Reactome Name: Antigen processing: Ubiquitination & Proteasome degradation See in Reactome R-HSA-8866654 R-HSA-8866654 Reactome Name: E3 ubiquitin ligases ubiquitinate target proteins See in Reactome	R-HSA-168256 R-HSA-168256 Reactome Name: Immune System See in Reactome R-HSA-392499 R-HSA-392499 Reactome Name: Metabolism of proteins See in Reactome R-HSA-983169 R-HSA-983169 Reactome Name: Class I MHC mediated antigen processing & presentation See in Reactome R-HSA-8852135 R-HSA-8852135 Reactome Name: Protein ubiquitination See in Reactome R-HSA-597592 R-HSA-597592 Reactome Name: Post-translational protein modification See in Reactome R-HSA-1280218 R-HSA-1280218 Reactome Name: Adaptive Immune System See in Reactome	Immune System Metabolism of proteins	R-HSA-8852130 ( R-HSA-8866652 ) R-HSA-8852130 Reaction Name: UBA1 conjugates ubiquitin to nuclear E2 enzymes See in Reactome R-HSA-8942099 ( R-HSA-8866654 ) R-HSA-8942099 Reaction Name: RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B See in Reactome R-HSA-8942101 ( R-HSA-8866654 ) R-HSA-8942101 Reaction Name: RNF20:RNF40 monoubiquitinates Histone H2B See in Reactome R-HSA-983140 ( R-HSA-983168 ) R-HSA-983140 Reaction Name: Transfer of Ub from E2 to substrate and release of E2 See in Reactome R-HSA-983152 ( R-HSA-983168 ) R-HSA-983152 Reaction Name: Transfer of ubiquitin from E1 to E2 See in Reactome R-HSA-983156 ( R-HSA-983168 ) R-HSA-983156 Reaction Name: Polyubiquitination of substrate See in Reactome R-HSA-983157 ( R-HSA-983168 ) R-HSA-983157 Reaction Name: Interaction of E3 with substrate and E2-Ub complex See in Reactome