DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0009549)

Number of enzymes:	3
Number of disease:	1
Number of reactomes:	3
Number of reactions:	6

Search results (Disease ID: MONDO:0009549)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0009549	RPE65	Q16518	3.1.1.64 5.3.3.22	R-HSA-2453902 R-HSA-2453902 Reactome Name: The canonical retinoid cycle in rods (twilight vision) See in Reactome	R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome	Sensory Perception	R-HSA-2453833 ( R-HSA-2453902 ) R-HSA-2453833 Reaction Name: RPE65 isomero-hydrolyses atREs to 11cROL See in Reactome
MONDO:0009549	ABCA4	P78363	7.6.2.1	R-HSA-382556 R-HSA-382556 Reactome Name: ABC-family proteins mediated transport See in Reactome R-HSA-2453902 R-HSA-2453902 Reactome Name: The canonical retinoid cycle in rods (twilight vision) See in Reactome	R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome R-HSA-382551 R-HSA-382551 Reactome Name: Transport of small molecules See in Reactome	Sensory Perception Transport of small molecules	R-HSA-1467466 ( R-HSA-2453902; R-HSA-382556 ) R-HSA-1467466 Reaction Name: ABCA4 mediates atRAL transport See in Reactome R-HSA-2466749 ( R-HSA-2453902 ) R-HSA-2466749 Reaction Name: ABCA4 transports NRPE from photoreceptor outer segment membrane to cytosol See in Reactome
MONDO:0009549	LRAT	O95237	2.3.1.135	R-HSA-975634 R-HSA-975634 Reactome Name: Retinoid metabolism and transport See in Reactome R-HSA-2453902 R-HSA-2453902 Reactome Name: The canonical retinoid cycle in rods (twilight vision) See in Reactome	R-HSA-6806667 R-HSA-6806667 Reactome Name: Metabolism of fat-soluble vitamins See in Reactome R-HSA-196854 R-HSA-196854 Reactome Name: Metabolism of vitamins and cofactors See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-2187338 R-HSA-2187338 Reactome Name: Visual phototransduction See in Reactome R-HSA-9709957 R-HSA-9709957 Reactome Name: Sensory Perception See in Reactome	Metabolism Sensory Perception	R-HSA-2404137 ( R-HSA-975634 ) R-HSA-2404137 Reaction Name: LRAT esterifies RBP1:atROL and FACYLs to atREs See in Reactome R-HSA-2453855 ( R-HSA-2453902 ) R-HSA-2453855 Reaction Name: LRAT esterifies RBP1:atROL and FACYLs to atREs See in Reactome R-HSA-975608 ( R-HSA-975634 ) R-HSA-975608 Reaction Name: LRAT esterifies RBP2:atROL and FACYLs to atREs See in Reactome