DAR - Bologna Biocomputing Group

Search summary (Disease ID: MONDO:0008280)

Number of enzymes:	1
Number of disease:	1
Number of reactomes:	4
Number of reactions:	7

Search results (Disease ID: MONDO:0008280)

DiseaseID	Gene	UniProt	EC numbers	Reactomes	Expanded Reactomes	Reactome roots	Reactions
MONDO:0008280	STK11	Q15831	2.7.11.1	R-HSA-163680 R-HSA-163680 Reactome Name: AMPK inhibits chREBP transcriptional activation activity See in Reactome R-HSA-6804756 R-HSA-6804756 Reactome Name: Regulation of TP53 Activity through Phosphorylation See in Reactome R-HSA-380972 R-HSA-380972 Reactome Name: Energy dependent regulation of mTOR by LKB1-AMPK See in Reactome R-HSA-9614657 R-HSA-9614657 Reactome Name: FOXO-mediated transcription of cell death genes See in Reactome	R-HSA-3700989 R-HSA-3700989 Reactome Name: Transcriptional Regulation by TP53 See in Reactome R-HSA-5633007 R-HSA-5633007 Reactome Name: Regulation of TP53 Activity See in Reactome R-HSA-9614085 R-HSA-9614085 Reactome Name: FOXO-mediated transcription See in Reactome R-HSA-74160 R-HSA-74160 Reactome Name: Gene expression (Transcription) See in Reactome R-HSA-163685 R-HSA-163685 Reactome Name: Integration of energy metabolism See in Reactome R-HSA-165159 R-HSA-165159 Reactome Name: MTOR signalling See in Reactome R-HSA-212436 R-HSA-212436 Reactome Name: Generic Transcription Pathway See in Reactome R-HSA-1430728 R-HSA-1430728 Reactome Name: Metabolism See in Reactome R-HSA-162582 R-HSA-162582 Reactome Name: Signal Transduction See in Reactome R-HSA-73857 R-HSA-73857 Reactome Name: RNA Polymerase II Transcription See in Reactome	Gene expression (Transcription) Metabolism Signal Transduction	R-HSA-164151 ( R-HSA-163680 ) R-HSA-164151 Reaction Name: LKB1 phosphorylates the alpha subunit of AMPK heterotrimer See in Reactome R-HSA-200421 ( R-HSA-380972 ) R-HSA-200421 Reaction Name: Activation of cytosolic AMPK by phosphorylation See in Reactome R-HSA-3222006 ( R-HSA-6804756 ) R-HSA-3222006 Reaction Name: STK11 (LKB1) phosphorylates NUAK1 See in Reactome R-HSA-3222020 ( R-HSA-6804756 ) R-HSA-3222020 Reaction Name: NUAK1 phosphorylates TP53 See in Reactome R-HSA-380942 ( R-HSA-380972 ) R-HSA-380942 Reaction Name: LKB1 forms a trimeric complex with STRAD and MO25 See in Reactome R-HSA-6805035 ( R-HSA-6804756 ) R-HSA-6805035 Reaction Name: TP53 binds STK11 and NUAK1 See in Reactome R-HSA-9625378 ( R-HSA-9614657 ) R-HSA-9625378 Reaction Name: STK11 gene transcription is stimulated by FOXO3,FOXO4 See in Reactome